27725_FusoPortal_Gene_2814

Protein

27725_FusoPortal_Gene_2814

Length

400 amino acids

Protein family membership

Threonine dehydratase, catabolic (IPR005789)

Homologous superfamilies

Homologous superfamily
4 - 313
Tryptophan synthase beta subunit-like PLP-dependent enzyme (IPR036052)

1 50 100 150 200 250 300 350 400 400

Domains and repeats

Domain
17 - 304
Pyridoxal-phosphate dependent enzyme (IPR001926)

1 50 100 150 200 250 300 350 400 400

Detailed signature matches

IPR036052

Tryptophan synthase beta subunit-like PLP-dependent enzyme
1. SSF53686 (Tryptopha...)
  
  4 - 313
  
  SUPERFAMILY
  SSF53686 (Tryptophan synthase beta subunit-like PLP-dependent enzymes)
IPR005789

Threonine dehydratase, catabolic
1. TIGR01127
  
  22 - 399
  
  TIGRFAMs
  TIGR01127 (TIGR01127)
IPR001926

Pyridoxal-phosphate dependent enzyme
1. PF00291 (PALP)
  
  17 - 304
  
  Pfam
  PF00291 (PALP)

no IPR

Unintegrated signatures

G3DSA:3.30.70...

325 - 399

GENE3D
G3DSA:3.30.70.260 (G3DSA:3.30.70.260)
G3DSA:3.40.50...

134 - 324

GENE3D
G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)

29 - 133

GENE3D
G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)
PTHR43419 (FAMILY N...)

2 - 398

PANTHER
PTHR43419 (FAMILY NOT NAMED)
PTHR43419:SF8 (THRE...)

2 - 398

PANTHER
PTHR43419:SF8 (THREONINE AMMONIA-LYASE)
SSF55021 (ACT-like)

325 - 395

SUPERFAMILY
SSF55021 (ACT-like)
cd01562 (Thr-dehyd)

5 - 308

CDD
cd01562 (Thr-dehyd)

Residue annotation

tetramer interface...

5L

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

6E

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

9K

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

12K

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

13E

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

44N

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

45L

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

191K

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

192S

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

261A

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

264I

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

265L

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

268M

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

272K

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

273V

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

274V

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

305G

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

306N

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

307I

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)

308D

tetramer interface
5L, 6E, 9K, 12K, 13E, 44N, 45L, 191K, 192S, 261A, 264I, 265L, 268M, 272K, 273V, 274V, 305G, 306N, 307I, 308D
CDD
cd01562 (Thr-dehyd)
catalytic residue ...

52K

catalytic residue
52K
CDD
cd01562 (Thr-dehyd)
pyridoxal 5'-phosp...

52K

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

79N

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

178G

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

179G

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

180G

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

181G

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

182I

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

303S

pyridoxal 5'-phosphate binding site
52K, 79N, 178G, 179G, 180G, 181G, 182I, 303S
CDD
cd01562 (Thr-dehyd)

GO term prediction

Biological Process

GO:0006567 threonine catabolic process

Molecular Function

GO:0004794 L-threonine ammonia-lyase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

27725_FusoPortal_Gene_2814

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component