27725_FusoPortal_Gene_2882

Protein

27725_FusoPortal_Gene_2882

Length

237 amino acids

Protein family membership

DAGK family (IPR000829)

Homologous superfamilies

Homologous superfamily
6 - 118
Diacylglycerol kinase (DAGK) superfamily (IPR036945)
Homologous superfamily
95 - 234
Phosphatidic acid phosphatase type 2/haloperoxidase superfamily (IPR036938)

1 50 100 150 200 237

Domains and repeats

Domain
161 - 234
Phosphatidic acid phosphatase type 2/haloperoxidase (IPR000326)

1 50 100 150 200 237

Detailed signature matches

IPR036945

Diacylglycerol kinase (DAGK) superfamily
1. G3DSA:1.10.38...
  
  6 - 118
  
  GENE3D
  G3DSA:1.10.3830.10 (G3DSA:1.10.3830.10)
IPR036938

Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
1. SSF48317 (Acid phos...)
  
  95 - 234
  
  SUPERFAMILY
  SSF48317 (Acid phosphatase/Vanadium-dependent haloperoxidase)
IPR000829

DAGK family
1. PF01219 (DAGK_prokar)
  
  16 - 116
  
  Pfam
  PF01219 (DAGK_prokar)
IPR000326

Phosphatidic acid phosphatase type 2/haloperoxidase
1. PF01569 (PAP2)
  
  161 - 234
  
  Pfam
  PF01569 (PAP2)

no IPR

Unintegrated signatures

PTHR34299 (FAMILY N...)

2 - 121

PANTHER
PTHR34299 (FAMILY NOT NAMED)

178 - 203

PANTHER
PTHR34299 (FAMILY NOT NAMED)

141 - 151

PANTHER
PTHR34299 (FAMILY NOT NAMED)
cd14266 (UDPK_IM_PA...)

11 - 116

CDD
cd14266 (UDPK_IM_PAP2_like)

Residue annotation

trimer interface c...

15N

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

16A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

17A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

18F

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

19E

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

20G

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

21L

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

23E

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

24A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

52K

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

53Y

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

54E

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

56L

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

57S

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

60I

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

63T

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

67I

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

68A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

70L

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

71F

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

73T

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

74A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

75I

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

77S

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

78C

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

79V

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

81M

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

82V

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

89L

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

90A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

93A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

96I

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

99S

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

100A

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

103V

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

104T

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

107N

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

111V

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

114I

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)

115I

trimer interface
15N, 16A, 17A, 18F, 19E, 20G, 21L, 23E, 24A, 52K, 53Y, 54E, 56L, 57S, 60I, 63T, 67I, 68A, 70L, 71F, 73T, 74A, 75I, 77S, 78C, 79V, 81M, 82V, 89L, 90A, 93A, 96I, 99S, 100A, 103V, 104T, 107N, 111V, 114I, 115I
CDD
cd14266 (UDPK_IM_PAP2_like)
putative active si...

19E

putative active site
19E, 28E, 69E, 76E, 80D, 94K, 95D
CDD
cd14266 (UDPK_IM_PAP2_like)

28E

putative active site
19E, 28E, 69E, 76E, 80D, 94K, 95D
CDD
cd14266 (UDPK_IM_PAP2_like)

69E

putative active site
19E, 28E, 69E, 76E, 80D, 94K, 95D
CDD
cd14266 (UDPK_IM_PAP2_like)

76E

putative active site
19E, 28E, 69E, 76E, 80D, 94K, 95D
CDD
cd14266 (UDPK_IM_PAP2_like)

80D

putative active site
19E, 28E, 69E, 76E, 80D, 94K, 95D
CDD
cd14266 (UDPK_IM_PAP2_like)

94K

putative active site
19E, 28E, 69E, 76E, 80D, 94K, 95D
CDD
cd14266 (UDPK_IM_PAP2_like)

95D

putative active site
19E, 28E, 69E, 76E, 80D, 94K, 95D
CDD
cd14266 (UDPK_IM_PAP2_like)
Zn binding site cd...

28E

Zn binding site
28E, 76E
CDD
cd14266 (UDPK_IM_PAP2_like)

76E

Zn binding site
28E, 76E
CDD
cd14266 (UDPK_IM_PAP2_like)

GO term prediction

Biological Process

GO:0008610 lipid biosynthetic process
GO:0008654 phospholipid biosynthetic process

Molecular Function

GO:0016301 kinase activity

Cellular Component

GO:0016020 membrane

Filter view on

Entry type

Status

Per-residue features

27725_FusoPortal_Gene_2882

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component