27725_FusoPortal_Gene_660

Protein

27725_FusoPortal_Gene_660

Length

165 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
2 - 165
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily (IPR036571)

1 20 40 60 80 100 120 140 165

Domains and repeats

Domain
10 - 165
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IPR003526)

1 20 40 60 80 100 120 140 165

Detailed signature matches

IPR036571

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily
1. SSF69765 (IpsF-like)
  
  9 - 164
  
  SUPERFAMILY
  SSF69765 (IpsF-like)
2. G3DSA:3.30.13...
  
  2 - 165
  
  GENE3D
  G3DSA:3.30.1330.50 (G3DSA:3.30.1330.50)
IPR003526

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
1. PF02542 (YgbB)
  
  10 - 164
  
  Pfam
  PF02542 (YgbB)
2. cd00554 (MECDP_synt...)
  
  11 - 163
  
  CDD
  cd00554 (MECDP_synthase)
3. MF_00107 (IspF)
  
  10 - 165
  
  HAMAP
  MF_00107 (IspF)
4. TIGR00151
  
  11 - 165
  
  TIGRFAMs
  TIGR00151 (TIGR00151)
IPR020555

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site
1. PS01350 (ISPF)
  
  44 - 59
  
  PROSITE patterns
  PS01350 (ISPF)

no IPR

Unintegrated signatures

PTHR43181 (FAMILY N...)

6 - 165

PANTHER
PTHR43181 (FAMILY NOT NAMED)

Residue annotation

homotrimer interac...

11R

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

12I

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

14N

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

16Y

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

18V

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

19H

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

20V

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

24G

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

59G

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

61L

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

62A

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

64G

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

65D

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

102N

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

104D

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

106I

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

113K

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

115K

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

137S

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

139K

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

140A

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

143E

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

144E

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

145K

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

158Y

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

160V

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)

162L

homotrimer interaction site
11R, 12I, 14N, 16Y, 18V, 19H, 20V, 24G, 59G, 61L, 62A, 64G, 65D, 102N, 104D, 106I, 113K, 115K, 137S, 139K, 140A, 143E, 144E, 145K, 158Y, 160V, 162L
CDD
cd00554 (MECDP_synthase)
zinc binding site ...

17D

zinc binding site
17D, 19H, 51H
CDD
cd00554 (MECDP_synthase)

19H

zinc binding site
17D, 19H, 51H
CDD
cd00554 (MECDP_synthase)

51H

zinc binding site
17D, 19H, 51H
CDD
cd00554 (MECDP_synthase)
CDP-binding sites ...

65D

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

67G

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

109L

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

110Q

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

112P

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

113K

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

114V

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

115K

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

140A

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

141T

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

142T

CDP-binding sites
65D, 67G, 109L, 110Q, 112P, 113K, 114V, 115K, 140A, 141T, 142T
CDD
cd00554 (MECDP_synthase)

GO term prediction

Biological Process

GO:0016114 terpenoid biosynthetic process

Molecular Function

GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

27725_FusoPortal_Gene_660

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component