27725_FusoPortal_Gene_819

Protein

27725_FusoPortal_Gene_819

Length

274 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 267
Carbon-nitrogen hydrolase superfamily (IPR036526)

1 50 100 150 200 274

Domains and repeats

Domain
2 - 252
Carbon-nitrogen hydrolase (IPR003010)

1 50 100 150 200 274

Detailed signature matches

IPR036526

Carbon-nitrogen hydrolase superfamily
1. G3DSA:3.60.11...
  
  1 - 267
  
  GENE3D
  G3DSA:3.60.110.10 (G3DSA:3.60.110.10)
2. SSF56317 (Carbon-ni...)
  
  3 - 262
  
  SUPERFAMILY
  SSF56317 (Carbon-nitrogen hydrolase)
IPR003010

Carbon-nitrogen hydrolase
1. PS50263 (CN_HYDROLASE)
  
  2 - 245
  
  PROSITE profiles
  PS50263 (CN_HYDROLASE)
2. PF00795 (CN_hydrolase)
  
  5 - 252
  
  Pfam
  PF00795 (CN_hydrolase)

no IPR

Unintegrated signatures

PTHR23088 (NITRILAS...)

2 - 268

PANTHER
PTHR23088 (NITRILASE-RELATED)
PTHR23088:SF30 (OME...)

2 - 268

PANTHER
PTHR23088:SF30 (OMEGA-AMIDASE NIT2)
cd07583 (nitrilase_5)

3 - 262

CDD
cd07583 (nitrilase_5)

Residue annotation

catalytic triad cd...

44E

catalytic triad
44E, 118K, 152C
CDD
cd07583 (nitrilase_5)

118K

catalytic triad
44E, 118K, 152C
CDD
cd07583 (nitrilase_5)

152C

catalytic triad
44E, 118K, 152C
CDD
cd07583 (nitrilase_5)
putative active si...

44E

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

118K

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

122Y

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

127E

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

152C

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

153Y

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

155I

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

156R

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)

177D

putative active site
44E, 118K, 122Y, 127E, 152C, 153Y, 155I, 156R, 177D
CDD
cd07583 (nitrilase_5)
putative dimer int...

119M

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

120H

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

121L

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

122Y

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

126D

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

133S

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

134G

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

135N

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

153Y

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

155I

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

156R

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

157F

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

158C

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

159E

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

162R

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

163I

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

188T

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

189L

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

191Q

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

192A

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

193R

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

195I

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

196E

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

217G

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

218H

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

259R

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

260D

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

261R

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

262H

putative dimer interface
119M, 120H, 121L, 122Y, 126D, 133S, 134G, 135N, 153Y, 155I, 156R, 157F, 158C, 159E, 162R, 163I, 188T, 189L, 191Q, 192A, 193R, 195I, 196E, 217G, 218H, 259R, 260D, 261R, 262H
CDD
cd07583 (nitrilase_5)

GO term prediction

Biological Process

GO:0006807 nitrogen compound metabolic process

Molecular Function

GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

27725_FusoPortal_Gene_819

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component