2_1_31_FusoPortal_Gene_293

Protein

2_1_31_FusoPortal_Gene_293

Length

304 amino acids

Protein family membership

Aminotransferase class IV (IPR001544)
- Branched-chain aminotransferase (IPR033939)
  - Branched-chain amino acid aminotransferase I (IPR005785)

Homologous superfamilies

Homologous superfamily
5 - 294
Aminotransferase-like, PLP-dependent enzymes (IPR036038)

1 50 100 150 200 250 304

Domains and repeats

None predicted.

Detailed signature matches

IPR036038

Aminotransferase-like, PLP-dependent enzymes
1. SSF56752 (D-aminoac...)
  
  5 - 294
  
  SUPERFAMILY
  SSF56752 (D-aminoacid aminotransferase-like PLP-dependent enzymes)
IPR001544

Aminotransferase class IV
1. PF01063 (Aminotran_4)
  
  34 - 264
  
  Pfam
  PF01063 (Aminotran_4)
IPR033939

Branched-chain aminotransferase
1. cd01557 (BCAT_beta_...)
  
  21 - 291
  
  CDD
  cd01557 (BCAT_beta_family)
IPR005785

Branched-chain amino acid aminotransferase I
1. TIGR01122
  
  8 - 303
  
  TIGRFAMs
  TIGR01122 (TIGR01122)
IPR018300

Aminotransferase, class IV, conserved site
1. PS00770 (AA_TRANSFE...)
  
  191 - 220
  
  PROSITE patterns
  PS00770 (AA_TRANSFER_CLASS_4)

no IPR

Unintegrated signatures

G3DSA:3.20.10.10

140 - 292

GENE3D
G3DSA:3.20.10.10 (G3DSA:3.20.10.10)
G3DSA:3.30.47...

1 - 139

GENE3D
G3DSA:3.30.470.10 (G3DSA:3.30.470.10)
PTHR42743 (FAMILY N...)

4 - 294

PANTHER
PTHR42743 (FAMILY NOT NAMED)
PTHR42743:SF4 (SUBF...)

4 - 294

PANTHER
PTHR42743:SF4 (SUBFAMILY NOT NAMED)

Residue annotation

homodimer interfac...

21I

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

22H

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

23I

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

24L

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

27V

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

28V

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

29H

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

30Y

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

31G

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

33S

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

35F

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

65I

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

96R

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

98I

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

104F

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

105E

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

106L

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

110P

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

118A

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

159G

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

164S

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

166Q

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

170L

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)

184D

homodimer interface
21I, 22H, 23I, 24L, 27V, 28V, 29H, 30Y, 31G, 33S, 35F, 65I, 96R, 98I, 104F, 105E, 106L, 110P, 118A, 159G, 164S, 166Q, 170L, 184D
CDD
cd01557 (BCAT_beta_family)
substrate-cofactor...

30Y

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

35F

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

58R

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

108V

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

157K

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

162Y

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

191E

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

218I

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

219T

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)

255T

substrate-cofactor binding pocket
30Y, 35F, 58R, 108V, 157K, 162Y, 191E, 218I, 219T, 255T
CDD
cd01557 (BCAT_beta_family)
catalytic residue ...

157K

catalytic residue
157K
CDD
cd01557 (BCAT_beta_family)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009081 branched-chain amino acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004084 branched-chain-amino-acid transaminase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

2_1_31_FusoPortal_Gene_293

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component