2_1_31_FusoPortal_Gene_4

Protein

2_1_31_FusoPortal_Gene_4

Length

578 amino acids

Protein family membership

Peptidase S49, protease IV (IPR004634)

Homologous superfamilies

Homologous superfamily
51 - 174
ClpP/crotonase-like domain superfamily (IPR029045)
207 - 268
ClpP/crotonase-like domain superfamily (IPR029045)
305 - 420
ClpP/crotonase-like domain superfamily (IPR029045)
448 - 508
ClpP/crotonase-like domain superfamily (IPR029045)

1 100 200 300 400 500 578

Domains and repeats

Domain
127 - 276
Peptidase S49 (IPR002142)
328 - 517
Peptidase S49 (IPR002142)
Peptidase S49, SppA (IPR004635)

1 100 200 300 400 500 578

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  448 - 508
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
  
  305 - 420
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
  
  51 - 174
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
  
  207 - 268
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR004634

Peptidase S49, protease IV
1. PIRSF001217 (Protea...)
  
  5 - 568
  
  PIRSF
  PIRSF001217 (Protease_4_SppA)
IPR002142

Peptidase S49
1. PF01343 (Peptidase_S49)
  
  372 - 517
  
  Pfam
  PF01343 (Peptidase_S49)
  
  127 - 276
  
  Pfam
  PF01343 (Peptidase_S49)
IPR004635

Peptidase S49, SppA
1. TIGR00706
  
  328 - 517
  
  TIGRFAMs
  TIGR00706 (TIGR00706)

no IPR

Unintegrated signatures

G3DSA:3.40.17...

181 - 267

GENE3D
G3DSA:3.40.1750.10 (G3DSA:3.40.1750.10)
G3DSA:3.90.22...

43 - 180

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)

296 - 540

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
PTHR33209 (FAMILY N...)

21 - 569

PANTHER
PTHR33209 (FAMILY NOT NAMED)
cd07018 (S49_SppA_6...)

57 - 278

CDD
cd07018 (S49_SppA_67K_type)
cd07023 (S49_Sppa_N_C)

305 - 513

CDD
cd07023 (S49_Sppa_N_C)

Residue annotation

tandem repeat inte...

62A

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

104K

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

141R

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

156P

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

160S

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

168Y

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

169F

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

170R

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

171E

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

222Y

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

246D

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

247G

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

248D

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

250V

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)

253S

tandem repeat interface
62A, 104K, 141R, 156P, 160S, 168Y, 169F, 170R, 171E, 222Y, 246D, 247G, 248D, 250V, 253S
CDD
cd07018 (S49_SppA_67K_type)
oligomer interface...

83Y

oligomer interface
83Y, 90K, 116E, 220L, 224N
CDD
cd07018 (S49_SppA_67K_type)

90K

oligomer interface
83Y, 90K, 116E, 220L, 224N
CDD
cd07018 (S49_SppA_67K_type)

116E

oligomer interface
83Y, 90K, 116E, 220L, 224N
CDD
cd07018 (S49_SppA_67K_type)

220L

oligomer interface
83Y, 90K, 116E, 220L, 224N
CDD
cd07018 (S49_SppA_67K_type)

224N

oligomer interface
83Y, 90K, 116E, 220L, 224N
CDD
cd07018 (S49_SppA_67K_type)
active site residu...

141R

active site residues
141R
CDD
cd07018 (S49_SppA_67K_type)
tandem repeat inte...

311E

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

352R

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

389S

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

404D

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

406N

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

417V

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

465Y

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

489G

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

490R

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

491V

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

493T

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)

496E

tandem repeat interface
311E, 352R, 389S, 404D, 406N, 417V, 465Y, 489G, 490R, 491V, 493T, 496E
CDD
cd07023 (S49_Sppa_N_C)
oligomer interface...

331N

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

338N

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

364D

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

429G

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

431N

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

432V

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

433E

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

434K

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

435I

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

463K

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)

467D

oligomer interface
331N, 338N, 364D, 429G, 431N, 432V, 433E, 434K, 435I, 463K, 467D
CDD
cd07023 (S49_Sppa_N_C)
active site residu...

389S

active site residues
389S
CDD
cd07023 (S49_Sppa_N_C)

GO term prediction

Biological Process

GO:0006465 signal peptide processing
GO:0006508 proteolysis

Molecular Function

GO:0008233 peptidase activity

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features

2_1_31_FusoPortal_Gene_4

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component