2_1_31_FusoPortal_Gene_562

Protein

2_1_31_FusoPortal_Gene_562

Length

168 amino acids

Protein family membership

3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (IPR010023)

Homologous superfamilies

Homologous superfamily
1 - 168
HAD superfamily (IPR023214)
Homologous superfamily
1 - 162
HAD-like superfamily (IPR036412)

1 20 40 60 80 100 120 140 168

Domains and repeats

Domain
5 - 118
HAD-superfamily hydrolase,subfamily IIIA (IPR006549)

1 20 40 60 80 100 120 140 168

Detailed signature matches

IPR036412

HAD-like superfamily
1. SSF56784 (HAD-like)
  
  1 - 162
  
  SUPERFAMILY
  SSF56784 (HAD-like)
IPR023214

HAD superfamily
1. G3DSA:3.40.50...
  
  1 - 168
  
  GENE3D
  G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
IPR010023

3-deoxy-D-manno-octulosonate 8-phosphate phosphatase
1. TIGR01670
  
  4 - 156
  
  TIGRFAMs
  TIGR01670 (TIGR01670)
2. SFLDG01138 (C1.6.2:...)
  
  1 - 159
  
  SFLD
  SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)
3. PIRSF006118 (KDO8-P...)
  
  1 - 166
  
  PIRSF
  PIRSF006118 (KDO8-P_Ptase)
IPR006549

HAD-superfamily hydrolase,subfamily IIIA
1. TIGR01662
  
  5 - 118
  
  TIGRFAMs
  TIGR01662 (TIGR01662)

no IPR

Unintegrated signatures

PF08282 (Hydrolase_3)

75 - 142

Pfam
PF08282 (Hydrolase_3)
PTHR21485 (CMP-N-AC...)

2 - 163

PANTHER
PTHR21485 (CMP-N-ACETYLNEURAMINIC ACID SYNTHASE)
cd01630 (HAD_KDO-like)

4 - 149

CDD
cd01630 (HAD_KDO-like)

Residue annotation

HAD signature moti...

10D

HAD signature motif I
10D, 11V, 12D, 13G, 14T
CDD
cd01630 (HAD_KDO-like)

11V

HAD signature motif I
10D, 11V, 12D, 13G, 14T
CDD
cd01630 (HAD_KDO-like)

12D

HAD signature motif I
10D, 11V, 12D, 13G, 14T
CDD
cd01630 (HAD_KDO-like)

13G

HAD signature motif I
10D, 11V, 12D, 13G, 14T
CDD
cd01630 (HAD_KDO-like)

14T

HAD signature motif I
10D, 11V, 12D, 13G, 14T
CDD
cd01630 (HAD_KDO-like)
SFLDG01138

10D

SFLD_Res02
10D, 12D, 54T, 80K, 103D, 107D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

12D

SFLD_Res02
10D, 12D, 54T, 80K, 103D, 107D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

54T

SFLD_Res02
10D, 12D, 54T, 80K, 103D, 107D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

80K

SFLD_Res02
10D, 12D, 54T, 80K, 103D, 107D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

103D

SFLD_Res02
10D, 12D, 54T, 80K, 103D, 107D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

107D

SFLD_Res02
10D, 12D, 54T, 80K, 103D, 107D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)
active site cd01630

10D

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

11V

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

12D

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

13G

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

14T

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

54T

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

55G

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

80K

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

102G

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

103D

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

106N

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)

107D

active site
10D, 11V, 12D, 13G, 14T, 54T, 55G, 80K, 102G, 103D, 106N, 107D
CDD
cd01630 (HAD_KDO-like)
tetramer interface...

12D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

17D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

18G

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

19K

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

20I

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

21Y

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

22V

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

23D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

24D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

26D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

28S

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

29F

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

30K

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

31A

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

32F

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

33N

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

34V

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

35K

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

38F

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

42N

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

56K

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

59N

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

60I

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

63R

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

64R

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

67E

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

78K

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

103D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

104D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

105L

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

106N

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

108I

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

109G

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

122D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

126E

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

141D

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

145R

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)

149E

tetramer interface
12D, 17D, 18G, 19K, 20I, 21Y, 22V, 23D, 24D, 26D, 28S, 29F, 30K, 31A, 32F, 33N, 34V, 35K, 38F, 42N, 56K, 59N, 60I, 63R, 64R, 67E, 78K, 103D, 104D, 105L, 106N, 108I, 109G, 122D, 126E, 141D, 145R, 149E
CDD
cd01630 (HAD_KDO-like)
HAD signature moti...

54T

HAD signature motif II
54T
CDD
cd01630 (HAD_KDO-like)
HAD signature moti...

80K

HAD signature motif III
80K
CDD
cd01630 (HAD_KDO-like)
HAD signature moti...

102G

HAD signature motif IV
102G, 103D, 107D
CDD
cd01630 (HAD_KDO-like)

103D

HAD signature motif IV
102G, 103D, 107D
CDD
cd01630 (HAD_KDO-like)

107D

HAD signature motif IV
102G, 103D, 107D
CDD
cd01630 (HAD_KDO-like)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0019143 3-deoxy-manno-octulosonate-8-phosphatase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

2_1_31_FusoPortal_Gene_562

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component