2_1_31_FusoPortal_Gene_727

Protein

2_1_31_FusoPortal_Gene_727

Length

1,242 amino acids

Protein family membership

Phosphoribosylformylglycinamidine synthase, FGAM (IPR010141)

Homologous superfamilies

Homologous superfamily
189 - 436
PurM-like, N-terminal domain superfamily (IPR036921)
614 - 812
PurM-like, N-terminal domain superfamily (IPR036921)
Homologous superfamily
432 - 605
PurM-like, C-terminal domain superfamily (IPR036676)
813 - 921
PurM-like, C-terminal domain superfamily (IPR036676)
976 - 1,242
Class I glutamine amidotransferase-like (IPR029062)

1 200 400 600 800 1000 1242

Domains and repeats

Domain
438 - 589
PurM-like, C-terminal domain (IPR010918)

1 200 400 600 800 1000 1242

Detailed signature matches

IPR036921

PurM-like, N-terminal domain superfamily
1. SSF55326 (PurM N-te...)
  
  626 - 812
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  189 - 225
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  294 - 436
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
2. G3DSA:3.30.13...
  
  614 - 807
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
  
  199 - 431
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
IPR036676

PurM-like, C-terminal domain superfamily
1. SSF56042 (PurM C-te...)
  
  813 - 921
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
  
  438 - 605
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
2. G3DSA:3.90.65...
  
  432 - 605
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
  
  814 - 919
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
IPR029062

Class I glutamine amidotransferase-like
1. G3DSA:3.40.50...
  
  978 - 1,242
  
  GENE3D
  G3DSA:3.40.50.880 (G3DSA:3.40.50.880)
2. SSF52317 (Class I g...)
  
  976 - 1,241
  
  SUPERFAMILY
  SSF52317 (Class I glutamine amidotransferase-like)
IPR010141

Phosphoribosylformylglycinamidine synthase, FGAM
1. TIGR01857
  
  5 - 1,241
  
  TIGRFAMs
  TIGR01857 (TIGR01857)
IPR010918

PurM-like, C-terminal domain
1. PF02769 (AIRS_C)
  
  438 - 589
  
  Pfam
  PF02769 (AIRS_C)

no IPR

Unintegrated signatures

PF13507 (GATase_5)

979 - 1,241

Pfam
PF13507 (GATase_5)
PTHR10099 (PHOSPHOR...)

2 - 1,237

PANTHER
PTHR10099 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
PTHR10099:SF1 (PHOS...)

2 - 1,237

PANTHER
PTHR10099:SF1 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
cd01740 (GATase1_FG...)

982 - 1,238

CDD
cd01740 (GATase1_FGAR_AT)
cd02203 (PurL_repeat1)

208 - 597

CDD
cd02203 (PurL_repeat1)
cd02204 (PurL_repeat2)

680 - 906

CDD
cd02204 (PurL_repeat2)

Residue annotation

dimerization inter...

315L

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

316L

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

317M

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

318F

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

320N

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

345D

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

355Q

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

358R

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

361G

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

405S

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

416R

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

417M

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)

421A

dimerization interface
315L, 316L, 317M, 318F, 320N, 345D, 355Q, 358R, 361G, 405S, 416R, 417M, 421A
CDD
cd02203 (PurL_repeat1)
ATP binding site c...

341G

ATP binding site
341G, 345D, 403L, 404V, 405S
CDD
cd02203 (PurL_repeat1)

345D

ATP binding site
341G, 345D, 403L, 404V, 405S
CDD
cd02203 (PurL_repeat1)

403L

ATP binding site
341G, 345D, 403L, 404V, 405S
CDD
cd02203 (PurL_repeat1)

404V

ATP binding site
341G, 345D, 403L, 404V, 405S
CDD
cd02203 (PurL_repeat1)

405S

ATP binding site
341G, 345D, 403L, 404V, 405S
CDD
cd02203 (PurL_repeat1)
dimerization inter...

696A

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

697S

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

698A

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

699I

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

701W

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

726K

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

739L

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

742Q

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

745F

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

780K

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

794P

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

795T

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)

799F

dimerization interface
696A, 697S, 698A, 699I, 701W, 726K, 739L, 742Q, 745F, 780K, 794P, 795T, 799F
CDD
cd02204 (PurL_repeat2)
ATP binding site c...

722E

ATP binding site
722E, 726K, 778G, 779G, 780K
CDD
cd02204 (PurL_repeat2)

726K

ATP binding site
722E, 726K, 778G, 779G, 780K
CDD
cd02204 (PurL_repeat2)

778G

ATP binding site
722E, 726K, 778G, 779G, 780K
CDD
cd02204 (PurL_repeat2)

779G

ATP binding site
722E, 726K, 778G, 779G, 780K
CDD
cd02204 (PurL_repeat2)

780K

ATP binding site
722E, 726K, 778G, 779G, 780K
CDD
cd02204 (PurL_repeat2)
putative active si...

1,042G

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,043F

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,047D

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,083C

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,087Q

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,149S

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,150H

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,211M

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,213H

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,214S

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,215E

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,216R

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214S, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)
catalytic triad cd...

1,083C

catalytic triad
1,083C, 1,213H, 1,215E
CDD
cd01740 (GATase1_FGAR_AT)

1,213H

catalytic triad
1,083C, 1,213H, 1,215E
CDD
cd01740 (GATase1_FGAR_AT)

1,215E

catalytic triad
1,083C, 1,213H, 1,215E
CDD
cd01740 (GATase1_FGAR_AT)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

2_1_31_FusoPortal_Gene_727

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component