49185_FusoPortal_Gene_1286

Protein

49185_FusoPortal_Gene_1286

Length

276 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 262
Carbon-nitrogen hydrolase superfamily (IPR036526)

1 50 100 150 200 250 276

Domains and repeats

Domain
1 - 242
Carbon-nitrogen hydrolase (IPR003010)

1 50 100 150 200 250 276

Detailed signature matches

IPR036526

Carbon-nitrogen hydrolase superfamily
1. G3DSA:3.60.11...
  
  1 - 262
  
  GENE3D
  G3DSA:3.60.110.10 (G3DSA:3.60.110.10)
2. SSF56317 (Carbon-ni...)
  
  1 - 257
  
  SUPERFAMILY
  SSF56317 (Carbon-nitrogen hydrolase)
IPR003010

Carbon-nitrogen hydrolase
1. PS50263 (CN_HYDROLASE)
  
  1 - 242
  
  PROSITE profiles
  PS50263 (CN_HYDROLASE)
2. PF00795 (CN_hydrolase)
  
  5 - 237
  
  Pfam
  PF00795 (CN_hydrolase)

no IPR

Unintegrated signatures

PTHR43674 (FAMILY N...)

1 - 269

PANTHER
PTHR43674 (FAMILY NOT NAMED)
PTHR43674:SF6 (SUBF...)

1 - 269

PANTHER
PTHR43674:SF6 (SUBFAMILY NOT NAMED)
cd07586 (nitrilase_8)

2 - 267

CDD
cd07586 (nitrilase_8)

Residue annotation

catalytic triad cd...

41E

catalytic triad
41E, 105K, 141C
CDD
cd07586 (nitrilase_8)

105K

catalytic triad
41E, 105K, 141C
CDD
cd07586 (nitrilase_8)

141C

catalytic triad
41E, 105K, 141C
CDD
cd07586 (nitrilase_8)
putative active si...

41E

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

105K

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

109P

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

116E

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

141C

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

142E

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

144A

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

145W

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)

166N

putative active site
41E, 105K, 109P, 116E, 141C, 142E, 144A, 145W, 166N
CDD
cd07586 (nitrilase_8)
putative dimer int...

106V

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

107Y

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

108L

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

109P

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

115S

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

122A

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

123G

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

124E

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

142E

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

144A

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

145W

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

146H

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

147Q

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

148S

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

151Y

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

152I

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

184A

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

185L

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

187K

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

188S

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

189S

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

191I

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

192S

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

213G

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

214N

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

257A

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

258E

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

259K

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

260L

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

261D

putative dimer interface
106V, 107Y, 108L, 109P, 115S, 122A, 123G, 124E, 142E, 144A, 145W, 146H, 147Q, 148S, 151Y, 152I, 184A, 185L, 187K, 188S, 189S, 191I, 192S, 213G, 214N, 257A, 258E, 259K, 260L, 261D
CDD
cd07586 (nitrilase_8)

GO term prediction

Biological Process

GO:0006807 nitrogen compound metabolic process

Molecular Function

GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_1286

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component