49185_FusoPortal_Gene_1577

Protein

49185_FusoPortal_Gene_1577

Length

306 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
2 - 305
Carbon-nitrogen hydrolase superfamily (IPR036526)

1 50 100 150 200 250 306

Domains and repeats

Domain
8 - 281
Carbon-nitrogen hydrolase (IPR003010)

1 50 100 150 200 250 306

Detailed signature matches

IPR036526

Carbon-nitrogen hydrolase superfamily
1. G3DSA:3.60.11...
  
  2 - 305
  
  GENE3D
  G3DSA:3.60.110.10 (G3DSA:3.60.110.10)
2. SSF56317 (Carbon-ni...)
  
  6 - 304
  
  SUPERFAMILY
  SSF56317 (Carbon-nitrogen hydrolase)
IPR003010

Carbon-nitrogen hydrolase
1. PS50263 (CN_HYDROLASE)
  
  8 - 278
  
  PROSITE profiles
  PS50263 (CN_HYDROLASE)
2. PF00795 (CN_hydrolase)
  
  9 - 281
  
  Pfam
  PF00795 (CN_hydrolase)

no IPR

Unintegrated signatures

PTHR23088 (NITRILAS...)

5 - 306

PANTHER
PTHR23088 (NITRILASE-RELATED)
PTHR23088:SF5 (NITR...)

5 - 306

PANTHER
PTHR23088:SF5 (NITRILASE)
cd07564 (nitrilases...)

8 - 306

CDD
cd07564 (nitrilases_CHs)

Residue annotation

catalytic triad cd...

48E

catalytic triad
48E, 137K, 171C
CDD
cd07564 (nitrilases_CHs)

137K

catalytic triad
48E, 137K, 171C
CDD
cd07564 (nitrilases_CHs)

171C

catalytic triad
48E, 137K, 171C
CDD
cd07564 (nitrilases_CHs)
putative active si...

48E

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)

137K

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)

141T

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)

144E

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)

171C

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)

172W

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)

174S

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)

175Y

putative active site
48E, 137K, 141T, 144E, 171C, 172W, 174S, 175Y
CDD
cd07564 (nitrilases_CHs)
putative dimer int...

138L

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

139K

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

140P

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

141T

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

143A

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

150D

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

151A

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

152D

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

172W

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

174S

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

175Y

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

176M

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

177P

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

178L

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

180R

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

181V

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

204A

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

205T

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

207R

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

208H

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

209I

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

211I

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

212E

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

249G

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

250G

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

293H

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

294Y

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

295S

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

296R

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

297P

putative dimer interface
138L, 139K, 140P, 141T, 143A, 150D, 151A, 152D, 172W, 174S, 175Y, 176M, 177P, 178L, 180R, 181V, 204A, 205T, 207R, 208H, 209I, 211I, 212E, 249G, 250G, 293H, 294Y, 295S, 296R, 297P
CDD
cd07564 (nitrilases_CHs)

GO term prediction

Biological Process

GO:0006807 nitrogen compound metabolic process

Molecular Function

GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_1577

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component