49185_FusoPortal_Gene_15

Protein

49185_FusoPortal_Gene_15

Length

413 amino acids

Protein family membership

Peptidase M20 (IPR002933)
- Peptidase M20B, tripeptide aminopeptidase (IPR010161)

Homologous superfamilies

Homologous superfamily
210 - 321
Bacterial exopeptidase dimerisation domain (IPR036264)

1 50 100 150 200 250 300 350 413

Domains and repeats

Domain
207 - 308
Peptidase M20, dimerisation domain (IPR011650)

1 50 100 150 200 250 300 350 413

Detailed signature matches

IPR036264

Bacterial exopeptidase dimerisation domain
1. SSF55031 (Bacterial...)
  
  210 - 321
  
  SUPERFAMILY
  SSF55031 (Bacterial exopeptidase dimerisation domain)
IPR002933

Peptidase M20
1. PF01546 (Peptidase_M20)
  
  140 - 403
  
  Pfam
  PF01546 (Peptidase_M20)
IPR010161

Peptidase M20B, tripeptide aminopeptidase
1. PIRSF037215 (Peptid...)
  
  1 - 409
  
  PIRSF
  PIRSF037215 (Peptidase_T)
2. PTHR42994:SF1 (PEPT...)
  
  2 - 407
  
  PANTHER
  PTHR42994:SF1 (PEPTIDASE T)
3. TIGR01882
  
  2 - 405
  
  TIGRFAMs
  TIGR01882 (TIGR01882)
4. cd03892 (M20_peptT)
  
  4 - 404
  
  CDD
  cd03892 (M20_peptT)
5. MF_00550 (Aminopept...)
  
  1 - 405
  
  HAMAP
  MF_00550 (Aminopeptidase_M20)
IPR011650

Peptidase M20, dimerisation domain
1. PF07687 (M20_dimer)
  
  207 - 308
  
  Pfam
  PF07687 (M20_dimer)
IPR001261

ArgE/DapE/ACY1/CPG2/YscS, conserved site
1. PS00759 (ARGE_DAPE_...)
  
  139 - 178
  
  PROSITE patterns
  PS00759 (ARGE_DAPE_CPG2_2)
2. PS00758 (ARGE_DAPE_...)
  
  73 - 82
  
  PROSITE patterns
  PS00758 (ARGE_DAPE_CPG2_1)

no IPR

Unintegrated signatures

G3DSA:3.40.63...

1 - 413

GENE3D
G3DSA:3.40.630.10 (G3DSA:3.40.630.10)
PTHR42994 (FAMILY N...)

2 - 407

PANTHER
PTHR42994 (FAMILY NOT NAMED)
SSF53187 (Zn-depend...)

323 - 407

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

1 - 211

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

Residue annotation

metal binding site...

78H

metal binding site
78H, 141D, 175E, 176E, 198D, 380H
CDD
cd03892 (M20_peptT)

141D

metal binding site
78H, 141D, 175E, 176E, 198D, 380H
CDD
cd03892 (M20_peptT)

175E

metal binding site
78H, 141D, 175E, 176E, 198D, 380H
CDD
cd03892 (M20_peptT)

176E

metal binding site
78H, 141D, 175E, 176E, 198D, 380H
CDD
cd03892 (M20_peptT)

198D

metal binding site
78H, 141D, 175E, 176E, 198D, 380H
CDD
cd03892 (M20_peptT)

380H

metal binding site
78H, 141D, 175E, 176E, 198D, 380H
CDD
cd03892 (M20_peptT)
dimer interface cd...

84T

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

225H

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

226P

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

227G

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

229A

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

230K

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

231N

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

233M

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

235N

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

237I

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

238L

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

241M

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

244N

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

253P

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

254E

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

255Y

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

256T

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

257E

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

262F

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

264L

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

265L

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

266N

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

267D

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

268M

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

269K

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

270G

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

271T

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

272V

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

354R

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

380H

dimer interface
84T, 225H, 226P, 227G, 229A, 230K, 231N, 233M, 235N, 237I, 238L, 241M, 244N, 253P, 254E, 255Y, 256T, 257E, 262F, 264L, 265L, 266N, 267D, 268M, 269K, 270G, 271T, 272V, 354R, 380H
CDD
cd03892 (M20_peptT)

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0008152 metabolic process

Molecular Function

GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0045148 tripeptide aminopeptidase activity

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_15

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component