49185_FusoPortal_Gene_1749

Protein

49185_FusoPortal_Gene_1749

Length

497 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)
- Drug resistance transporter EmrB/QacA subfamily (IPR004638)

Homologous superfamilies

Homologous superfamily
9 - 200
MFS transporter superfamily (IPR036259)
248 - 419
MFS transporter superfamily (IPR036259)
468 - 492
MFS transporter superfamily (IPR036259)

1 50 100 150 200 250 300 350 400 450 497

Domains and repeats

Domain
10 - 495
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 497

Detailed signature matches

IPR036259

MFS transporter superfamily
1. SSF103473 (MFS gene...)
  
  9 - 200
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  468 - 492
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  248 - 419
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  14 - 409
  
  Pfam
  PF07690 (MFS_1)
IPR004638

Drug resistance transporter EmrB/QacA subfamily
1. TIGR00711
  
  8 - 489
  
  TIGRFAMs
  TIGR00711 (TIGR00711)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  10 - 495
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  11 - 419
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

258 - 495

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

8 - 196

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
PR01036 (TCRTETB)

13 - 37

PRINTS
PR01036 (TCRTETB)

104 - 124

PRINTS
PR01036 (TCRTETB)

134 - 158

PRINTS
PR01036 (TCRTETB)
PTHR23501 (FAMILY N...)

6 - 495

PANTHER
PTHR23501 (FAMILY NOT NAMED)
PTHR23501:SF69 (MUL...)

6 - 495

PANTHER
PTHR23501:SF69 (MULTIDRUG EXPORT PROTEIN EMRB-RELATED)

Residue annotation

putative substrate...

25S

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

28V

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

29N

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

30V

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

32L

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

33T

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

50I

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

53Y

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

54A

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

57E

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

61L

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

62P

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

64I

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

65G

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

111G

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

112A

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

115I

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

116P

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

119Q

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

120T

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

123L

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

135M

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

136G

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

139S

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

140M

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

146P

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

278S

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

281F

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

282F

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

285V

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

286V

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

289P

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

303S

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

307T

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

311G

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

314I

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

318A

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

368G

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

371L

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

372G

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

375F

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

379N

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

380T

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

383L

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

394A

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

395S

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

398Y

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

399N

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

402R

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

403N

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

406N

putative substrate translocation pore
25S, 28V, 29N, 30V, 32L, 33T, 50I, 53Y, 54A, 57E, 61L, 62P, 64I, 65G, 111G, 112A, 115I, 116P, 119Q, 120T, 123L, 135M, 136G, 139S, 140M, 146P, 278S, 281F, 282F, 285V, 286V, 289P, 303S, 307T, 311G, 314I, 318A, 368G, 371L, 372G, 375F, 379N, 380T, 383L, 394A, 395S, 398Y, 399N, 402R, 403N, 406N
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

49185_FusoPortal_Gene_1749

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component