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Entry type
Status
Per-residue features
Colour by
49185_FusoPortal_Gene_1788
Length
300 amino acids
Protein family membership
- DapA-like (IPR002220)
- 4-hydroxy-tetrahydrodipicolinate synthase, DapA (IPR005263)
Homologous superfamilies
-
Homologous superfamily1 - 298
- Aldolase-type TIM barrel (IPR013785)
1
50
100
150
200
250
300
300
Domains and repeats
None predicted.
Detailed signature matches
-
-
1 - 298
-
-
-
PF00701 (DHDPS)6 - 293
-
PIRSF001365 (DHDPS)1 - 300
-
PR00146 (DHPICSNTHASE)
-
PTHR12128 (DIHYDROD...)1 - 293
-
Residue annotation
-
inhibitor site cd...12P44F47G48T49N137Y165K
-
active site cd0040844F47G48T49N137Y165K209I
-
dimer interface cd...48Tdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)53Ydimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)54Idimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)85Sdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)86Tdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)110Sdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)111Fdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)118Edimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)122Hdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)274Kdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like)275Pdimer interface
48T, 53Y, 54I, 85S, 86T, 110S, 111F, 118E, 122H, 274K, 275P
CDD
cd00408 (DHDPS-like) -
catalytic residue ...165K
GO term prediction
Biological Process
GO:0008152 metabolic process
GO:0009089 lysine biosynthetic process via diaminopimelate
Molecular Function
GO:0003824 catalytic activity
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase
GO:0016829 lyase activity
Cellular Component
None predicted.