49185_FusoPortal_Gene_2158

Protein

49185_FusoPortal_Gene_2158

Length

351 amino acids

Protein family membership

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic (IPR017846)

Homologous superfamilies

Homologous superfamily
5 - 71
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal (IPR023195)
Homologous superfamily
6 - 344
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily (IPR036087)

1 50 100 150 200 250 300 351

Domains and repeats

Domain
11 - 342
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like (IPR003200)

1 50 100 150 200 250 300 351

Detailed signature matches

IPR023195

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal
1. G3DSA:1.10.16...
  
  5 - 71
  
  GENE3D
  G3DSA:1.10.1610.10 (G3DSA:1.10.1610.10)
IPR036087

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily
1. SSF52733 (Nicotinat...)
  
  6 - 344
  
  SUPERFAMILY
  SSF52733 (Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT))
IPR017846

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic
1. MF_00230 (CobT)
  
  13 - 350
  
  HAMAP
  MF_00230 (CobT)
2. TIGR03160
  
  15 - 343
  
  TIGRFAMs
  TIGR03160 (TIGR03160)
IPR003200

Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like
1. cd02439 (DMB-PRT_CobT)
  
  31 - 342
  
  CDD
  cd02439 (DMB-PRT_CobT)
2. PF02277 (DBI_PRT)
  
  11 - 342
  
  Pfam
  PF02277 (DBI_PRT)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

72 - 331

GENE3D
G3DSA:3.40.50.10210 (G3DSA:3.40.50.10210)
PTHR43463 (FAMILY N...)

5 - 344

PANTHER
PTHR43463 (FAMILY NOT NAMED)
PTHR43463:SF1 (NICO...)

5 - 344

PANTHER
PTHR43463:SF1 (NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE)

Residue annotation

putative dimer int...

31K

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

32P

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

33N

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

34G

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

35S

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

36L

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

37G

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

38T

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

39L

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

78S

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

83Y

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

86I

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

87V

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

95I

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

96A

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

97A

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

100L

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

101L

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

103R

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

294E

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

308E

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

310F

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

311F

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

312N

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

313M

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

314R

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

315M

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

317L

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

325L

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

328P

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

332C

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

335E

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

336V

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

340M

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)

341K

putative dimer interface
31K, 32P, 33N, 34G, 35S, 36L, 37G, 38T, 39L, 78S, 83Y, 86I, 87V, 95I, 96A, 97A, 100L, 101L, 103R, 294E, 308E, 310F, 311F, 312N, 313M, 314R, 315M, 317L, 325L, 328P, 332C, 335E, 336V, 340M, 341K
CDD
cd02439 (DMB-PRT_CobT)
active site pocket...

32P

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

33N

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

77S

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

83Y

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

87V

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

176E

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

177M

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

178G

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

179I

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

180G

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

181N

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

182T

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

266G

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

267F

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

268I

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

293S

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

317L

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

318G

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

319E

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)

342T

active site pocket
32P, 33N, 77S, 83Y, 87V, 176E, 177M, 178G, 179I, 180G, 181N, 182T, 266G, 267F, 268I, 293S, 317L, 318G, 319E, 342T
CDD
cd02439 (DMB-PRT_CobT)
putative cataytic ...

319E

putative cataytic base
319E
CDD
cd02439 (DMB-PRT_CobT)

GO term prediction

Biological Process

GO:0009163 nucleoside biosynthetic process
GO:0009236 cobalamin biosynthetic process

Molecular Function

GO:0008939 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

49185_FusoPortal_Gene_2158

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component