49185_FusoPortal_Gene_2187

Protein

49185_FusoPortal_Gene_2187

Length

406 amino acids

Protein family membership

Exonuclease VII, large subunit (IPR003753)

Homologous superfamilies

None predicted.

Domains and repeats

Domain
7 - 102
OB-fold nucleic acid binding domain (IPR025824)
126 - 392
Exonuclease VII, large subunit, C-terminal (IPR020579)

1 50 100 150 200 250 300 350 406

Detailed signature matches

IPR003753

Exonuclease VII, large subunit
1. TIGR00237
  
  8 - 396
  
  TIGRFAMs
  TIGR00237 (TIGR00237)
2. MF_00378 (Exonuc_7_L)
  
  4 - 397
  
  HAMAP
  MF_00378 (Exonuc_7_L)
IPR025824

OB-fold nucleic acid binding domain
1. PF13742 (tRNA_anti_2)
  
  7 - 102
  
  Pfam
  PF13742 (tRNA_anti_2)
2. cd04489 (ExoVII_LU_OBF)
  
  29 - 102
  
  CDD
  cd04489 (ExoVII_LU_OBF)
IPR020579

Exonuclease VII, large subunit, C-terminal
1. PF02601 (Exonuc_VII_L)
  
  126 - 343
  
  Pfam
  PF02601 (Exonuc_VII_L)
  
  329 - 392
  
  Pfam
  PF02601 (Exonuc_VII_L)

no IPR

Unintegrated signatures

Coil

100 - 124

COILS
Coil (Coil)

305 - 347

COILS
Coil (Coil)
G3DSA:2.40.50...

3 - 120

GENE3D
G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
G3DSA:3.40.50...

129 - 237

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)

Residue annotation

generic binding su...

30F

generic binding surface II
30F, 78S, 80K, 82F, 102E
CDD
cd04489 (ExoVII_LU_OBF)

78S

generic binding surface II
30F, 78S, 80K, 82F, 102E
CDD
cd04489 (ExoVII_LU_OBF)

80K

generic binding surface II
30F, 78S, 80K, 82F, 102E
CDD
cd04489 (ExoVII_LU_OBF)

82F

generic binding surface II
30F, 78S, 80K, 82F, 102E
CDD
cd04489 (ExoVII_LU_OBF)

102E

generic binding surface II
30F, 78S, 80K, 82F, 102E
CDD
cd04489 (ExoVII_LU_OBF)
generic binding su...

35M

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

36S

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

37G

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

47Y

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

48F

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

49N

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

50L

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

52D

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

58K

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

59C

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

60A

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

62F

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

77D

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

84D

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

85V

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

86G

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

95Q

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

96I

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

97L

generic binding surface I
35M, 36S, 37G, 47Y, 48F, 49N, 50L, 52D, 58K, 59C, 60A, 62F, 77D, 84D, 85V, 86G, 95Q, 96I, 97L
CDD
cd04489 (ExoVII_LU_OBF)

GO term prediction

Biological Process

GO:0006308 DNA catabolic process

Molecular Function

GO:0003676 nucleic acid binding
GO:0008855 exodeoxyribonuclease VII activity

Cellular Component

GO:0009318 exodeoxyribonuclease VII complex

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_2187

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component