49185_FusoPortal_Gene_2309

Protein

49185_FusoPortal_Gene_2309

Length

168 amino acids

Protein family membership

3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (IPR010023)

Homologous superfamilies

Homologous superfamily
1 - 168
HAD superfamily (IPR023214)
Homologous superfamily
1 - 161
HAD-like superfamily (IPR036412)

1 20 40 60 80 100 120 140 168

Domains and repeats

Domain
3 - 116
HAD-superfamily hydrolase,subfamily IIIA (IPR006549)

1 20 40 60 80 100 120 140 168

Detailed signature matches

IPR036412

HAD-like superfamily
1. SSF56784 (HAD-like)
  
  1 - 161
  
  SUPERFAMILY
  SSF56784 (HAD-like)
IPR023214

HAD superfamily
1. G3DSA:3.40.50...
  
  1 - 168
  
  GENE3D
  G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
IPR010023

3-deoxy-D-manno-octulosonate 8-phosphate phosphatase
1. TIGR01670
  
  2 - 152
  
  TIGRFAMs
  TIGR01670 (TIGR01670)
2. SFLDG01138 (C1.6.2:...)
  
  2 - 157
  
  SFLD
  SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)
3. PIRSF006118 (KDO8-P...)
  
  1 - 164
  
  PIRSF
  PIRSF006118 (KDO8-P_Ptase)
IPR006549

HAD-superfamily hydrolase,subfamily IIIA
1. TIGR01662
  
  3 - 116
  
  TIGRFAMs
  TIGR01662 (TIGR01662)

no IPR

Unintegrated signatures

PF08282 (Hydrolase_3)

70 - 142

Pfam
PF08282 (Hydrolase_3)
PTHR21485 (CMP-N-AC...)

2 - 160

PANTHER
PTHR21485 (CMP-N-ACETYLNEURAMINIC ACID SYNTHASE)
cd01630 (HAD_KDO-like)

2 - 147

CDD
cd01630 (HAD_KDO-like)

Residue annotation

HAD signature moti...

8D

HAD signature motif I
8D, 9V, 10D, 11G, 12T
CDD
cd01630 (HAD_KDO-like)

9V

HAD signature motif I
8D, 9V, 10D, 11G, 12T
CDD
cd01630 (HAD_KDO-like)

10D

HAD signature motif I
8D, 9V, 10D, 11G, 12T
CDD
cd01630 (HAD_KDO-like)

11G

HAD signature motif I
8D, 9V, 10D, 11G, 12T
CDD
cd01630 (HAD_KDO-like)

12T

HAD signature motif I
8D, 9V, 10D, 11G, 12T
CDD
cd01630 (HAD_KDO-like)
active site cd01630

8D

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

9V

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

10D

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

11G

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

12T

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

52T

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

53G

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

78K

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

100G

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

101D

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

104N

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)

105D

active site
8D, 9V, 10D, 11G, 12T, 52T, 53G, 78K, 100G, 101D, 104N, 105D
CDD
cd01630 (HAD_KDO-like)
SFLDG01138

8D

SFLD_Res02
8D, 10D, 52T, 78K, 101D, 105D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

10D

SFLD_Res02
8D, 10D, 52T, 78K, 101D, 105D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

52T

SFLD_Res02
8D, 10D, 52T, 78K, 101D, 105D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

78K

SFLD_Res02
8D, 10D, 52T, 78K, 101D, 105D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

101D

SFLD_Res02
8D, 10D, 52T, 78K, 101D, 105D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)

105D

SFLD_Res02
8D, 10D, 52T, 78K, 101D, 105D
SFLD
SFLDG01138 (C1.6.2:_Deoxy-d-mannose-octul)
tetramer interface...

10D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

15N

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

16G

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

17K

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

18L

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

19Y

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

20M

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

21D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

22D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

24D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

26S

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

27L

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

28K

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

29A

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

30F

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

31D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

32V

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

33K

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

36F

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

40Q

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

54K

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

57V

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

58I

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

61R

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

62R

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

65E

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

76G

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

101D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

102D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

103I

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

104N

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

106L

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

107G

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

120N

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

124E

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

139D

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

143R

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)

147E

tetramer interface
10D, 15N, 16G, 17K, 18L, 19Y, 20M, 21D, 22D, 24D, 26S, 27L, 28K, 29A, 30F, 31D, 32V, 33K, 36F, 40Q, 54K, 57V, 58I, 61R, 62R, 65E, 76G, 101D, 102D, 103I, 104N, 106L, 107G, 120N, 124E, 139D, 143R, 147E
CDD
cd01630 (HAD_KDO-like)
HAD signature moti...

52T

HAD signature motif II
52T
CDD
cd01630 (HAD_KDO-like)
HAD signature moti...

78K

HAD signature motif III
78K
CDD
cd01630 (HAD_KDO-like)
HAD signature moti...

100G

HAD signature motif IV
100G, 101D, 105D
CDD
cd01630 (HAD_KDO-like)

101D

HAD signature motif IV
100G, 101D, 105D
CDD
cd01630 (HAD_KDO-like)

105D

HAD signature motif IV
100G, 101D, 105D
CDD
cd01630 (HAD_KDO-like)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0019143 3-deoxy-manno-octulosonate-8-phosphatase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_2309

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component