49185_FusoPortal_Gene_2633

Protein

49185_FusoPortal_Gene_2633

Length

1,241 amino acids

Protein family membership

Phosphoribosylformylglycinamidine synthase, FGAM (IPR010141)

Homologous superfamilies

Homologous superfamily
78 - 141
Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily (IPR036604)
418 - 657
PurM-like, C-terminal domain superfamily (IPR036676)
795 - 933
PurM-like, C-terminal domain superfamily (IPR036676)
Homologous superfamily
201 - 428
PurM-like, N-terminal domain superfamily (IPR036921)
617 - 807
PurM-like, N-terminal domain superfamily (IPR036921)
975 - 1,241
Class I glutamine amidotransferase-like (IPR029062)

1 200 400 600 800 1000 1241

Domains and repeats

Domain
439 - 588
PurM-like, C-terminal domain (IPR010918)
980 - 1,241
Glutamine amidotransferase (IPR017926)

1 200 400 600 800 1000 1241

Detailed signature matches

IPR036604

Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily
1. G3DSA:3.30.12...
  
  78 - 141
  
  GENE3D
  G3DSA:3.30.1280.10 (G3DSA:3.30.1280.10)
IPR036921

PurM-like, N-terminal domain superfamily
1. SSF55326 (PurM N-te...)
  
  302 - 428
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  201 - 227
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  630 - 807
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
2. G3DSA:3.30.13...
  
  617 - 794
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
  
  201 - 417
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
IPR036676

PurM-like, C-terminal domain superfamily
1. SSF56042 (PurM C-te...)
  
  813 - 933
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
  
  436 - 657
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
2. G3DSA:3.90.65...
  
  418 - 606
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
  
  795 - 887
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
IPR029062

Class I glutamine amidotransferase-like
1. G3DSA:3.40.50...
  
  977 - 1,241
  
  GENE3D
  G3DSA:3.40.50.880 (G3DSA:3.40.50.880)
2. SSF52317 (Class I g...)
  
  975 - 1,240
  
  SUPERFAMILY
  SSF52317 (Class I glutamine amidotransferase-like)
IPR010141

Phosphoribosylformylglycinamidine synthase, FGAM
1. TIGR01857
  
  4 - 1,240
  
  TIGRFAMs
  TIGR01857 (TIGR01857)
IPR010918

PurM-like, C-terminal domain
1. PF02769 (AIRS_C)
  
  439 - 588
  
  Pfam
  PF02769 (AIRS_C)
IPR017926

Glutamine amidotransferase
1. PS51273 (GATASE_TYPE_1)
  
  980 - 1,241
  
  PROSITE profiles
  PS51273 (GATASE_TYPE_1)

no IPR

Unintegrated signatures

Coil

17 - 37

COILS
Coil (Coil)
PF13507 (GATase_5)

978 - 1,240

Pfam
PF13507 (GATase_5)
PTHR10099 (PHOSPHOR...)

2 - 1,241

PANTHER
PTHR10099 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
PTHR10099:SF1 (PHOS...)

2 - 1,241

PANTHER
PTHR10099:SF1 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
cd01740 (GATase1_FG...)

981 - 1,237

CDD
cd01740 (GATase1_FGAR_AT)
cd02203 (PurL_repeat1)

210 - 598

CDD
cd02203 (PurL_repeat1)
cd02204 (PurL_repeat2)

681 - 918

CDD
cd02204 (PurL_repeat2)

Residue annotation

dimerization inter...

316L

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

317L

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

318M

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

319F

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

321N

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

346D

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

356Q

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

359R

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

362G

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

406C

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

417R

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

418M

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

422A

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406C, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)
ATP binding site c...

342G

ATP binding site
342G, 346D, 404H, 405V, 406C
CDD
cd02203 (PurL_repeat1)

346D

ATP binding site
342G, 346D, 404H, 405V, 406C
CDD
cd02203 (PurL_repeat1)

404H

ATP binding site
342G, 346D, 404H, 405V, 406C
CDD
cd02203 (PurL_repeat1)

405V

ATP binding site
342G, 346D, 404H, 405V, 406C
CDD
cd02203 (PurL_repeat1)

406C

ATP binding site
342G, 346D, 404H, 405V, 406C
CDD
cd02203 (PurL_repeat1)
dimerization inter...

697A

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

698S

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

699A

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

700I

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

702W

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

727K

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

740L

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

743Q

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

746F

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

781K

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

795P

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

796T

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)

800F

dimerization interface
697A, 698S, 699A, 700I, 702W, 727K, 740L, 743Q, 746F, 781K, 795P, 796T, 800F
CDD
cd02204 (PurL_repeat2)
ATP binding site c...

723E

ATP binding site
723E, 727K, 779G, 780G, 781K
CDD
cd02204 (PurL_repeat2)

727K

ATP binding site
723E, 727K, 779G, 780G, 781K
CDD
cd02204 (PurL_repeat2)

779G

ATP binding site
723E, 727K, 779G, 780G, 781K
CDD
cd02204 (PurL_repeat2)

780G

ATP binding site
723E, 727K, 779G, 780G, 781K
CDD
cd02204 (PurL_repeat2)

781K

ATP binding site
723E, 727K, 779G, 780G, 781K
CDD
cd02204 (PurL_repeat2)
putative active si...

1,041G

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,042F

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,046D

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,082C

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,086Q

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,148S

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,149H

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,210M

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,212H

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,213S

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,214E

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)

1,215R

putative active site
1,041G, 1,042F, 1,046D, 1,082C, 1,086Q, 1,148S, 1,149H, 1,210M, 1,212H, 1,213S, 1,214E, 1,215R
CDD
cd01740 (GATase1_FGAR_AT)
catalytic triad cd...

1,082C

catalytic triad
1,082C, 1,212H, 1,214E
CDD
cd01740 (GATase1_FGAR_AT)

1,212H

catalytic triad
1,082C, 1,212H, 1,214E
CDD
cd01740 (GATase1_FGAR_AT)

1,214E

catalytic triad
1,082C, 1,212H, 1,214E
CDD
cd01740 (GATase1_FGAR_AT)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_2633

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component