49185_FusoPortal_Gene_2642

Protein

49185_FusoPortal_Gene_2642

Length

391 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)
- Tetracycline resistance protein TetA/multidrug resistance protein MdtG (IPR001958)

Homologous superfamilies

Homologous superfamily
4 - 383
MFS transporter superfamily (IPR036259)

1 50 100 150 200 250 300 350 391

Domains and repeats

Domain
1 - 387
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 391

Detailed signature matches

IPR036259

MFS transporter superfamily
1. SSF103473 (MFS gene...)
  
  4 - 383
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  4 - 259
  
  Pfam
  PF07690 (MFS_1)
IPR001958

Tetracycline resistance protein TetA/multidrug resistance protein MdtG
1. PR01035 (TCRTETA)
  
  95 - 116
  
  PRINTS
  PR01035 (TCRTETA)
  
  125 - 147
  
  PRINTS
  PR01035 (TCRTETA)
  
  36 - 55
  
  PRINTS
  PR01035 (TCRTETA)
  
  334 - 357
  
  PRINTS
  PR01035 (TCRTETA)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  1 - 387
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  4 - 381
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

1 - 188

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

200 - 383

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
PTHR23504 (FAMILY N...)

17 - 375

PANTHER
PTHR23504 (FAMILY NOT NAMED)
PTHR23504:SF31 (MAJ...)

17 - 375

PANTHER
PTHR23504:SF31 (MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10)

Residue annotation

putative substrate...

15N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

18I

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

19H

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

20P

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

22T

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

23P

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

40F

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

43M

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

44S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

47N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

51S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

52P

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

54W

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

55G

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

101S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

102G

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

105L

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

106V

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

109L

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

110A

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

113S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

125L

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

126S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

129A

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

130A

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

136V

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

220E

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

223R

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

224V

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

227N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

228N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

231N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

245N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

249M

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

253G

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

256G

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

260N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

309Y

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

312N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

313A

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

316V

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

320Q

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

321S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

324T

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

334L

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

335S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

338F

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

339N

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

342K

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

343S

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

346M

putative substrate translocation pore
15N, 18I, 19H, 20P, 22T, 23P, 40F, 43M, 44S, 47N, 51S, 52P, 54W, 55G, 101S, 102G, 105L, 106V, 109L, 110A, 113S, 125L, 126S, 129A, 130A, 136V, 220E, 223R, 224V, 227N, 228N, 231N, 245N, 249M, 253G, 256G, 260N, 309Y, 312N, 313A, 316V, 320Q, 321S, 324T, 334L, 335S, 338F, 339N, 342K, 343S, 346M
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

49185_FusoPortal_Gene_2642

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component