49185_FusoPortal_Gene_3022

Protein

49185_FusoPortal_Gene_3022

Length

500 amino acids

Protein family membership

Carbohydrate kinase, FGGY (IPR000577)
- Glycerol kinase (IPR005999)

Homologous superfamilies

None predicted.

Domains and repeats

Domain
5 - 253
Carbohydrate kinase, FGGY, N-terminal (IPR018484)
263 - 451
Carbohydrate kinase, FGGY, C-terminal (IPR018485)

1 50 100 150 200 250 300 350 400 450 500 500

Detailed signature matches

IPR000577

Carbohydrate kinase, FGGY
1. PIRSF000538 (GlpK)
  
  3 - 500
  
  PIRSF
  PIRSF000538 (GlpK)
IPR005999

Glycerol kinase
1. TIGR01311
  
  4 - 497
  
  TIGRFAMs
  TIGR01311 (TIGR01311)
2. MF_00186 (Glycerol_kin)
  
  3 - 498
  
  HAMAP
  MF_00186 (Glycerol_kin)
IPR018484

Carbohydrate kinase, FGGY, N-terminal
1. PF00370 (FGGY_N)
  
  5 - 253
  
  Pfam
  PF00370 (FGGY_N)
IPR018485

Carbohydrate kinase, FGGY, C-terminal
1. PF02782 (FGGY_C)
  
  263 - 451
  
  Pfam
  PF02782 (FGGY_C)
IPR018483

Carbohydrate kinase, FGGY, conserved site
1. PS00445 (FGGY_KINAS...)
  
  363 - 383
  
  PROSITE patterns
  PS00445 (FGGY_KINASES_2)
2. PS00933 (FGGY_KINAS...)
  
  136 - 148
  
  PROSITE patterns
  PS00933 (FGGY_KINASES_1)

no IPR

Unintegrated signatures

G3DSA:3.30.42...

1 - 249

GENE3D
G3DSA:3.30.420.40 (G3DSA:3.30.420.40)

250 - 500

GENE3D
G3DSA:3.30.420.40 (G3DSA:3.30.420.40)
PTHR10196 (SUGAR KI...)

4 - 498

PANTHER
PTHR10196 (SUGAR KINASE)
PTHR10196:SF69 (GH1...)

4 - 498

PANTHER
PTHR10196:SF69 (GH12641P)
SSF53067 (Actin-lik...)

4 - 256

SUPERFAMILY
SSF53067 (Actin-like ATPase domain)

256 - 498

SUPERFAMILY
SSF53067 (Actin-like ATPase domain)
cd07786 (FGGY_EcGK_...)

5 - 492

CDD
cd07786 (FGGY_EcGK_like)

Residue annotation

N- and C-terminal ...

5Y

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

6I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

8A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

10D

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

13T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

14T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

17R

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

19V

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

21F

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

22D

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

25Q

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

27I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

43G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

75I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

76G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

77I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

78G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

79I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

80T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

81N

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

82Q

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

83R

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

103W

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

104Q

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

106R

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

109A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

113D

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

126K

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

129T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

130G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

131L

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

132V

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

134D

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

136Y

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

137F

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

184Y

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

185T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

188S

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

189R

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

195I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

196K

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

198L

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

220D

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

221S

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

222S

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

223G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

241A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

242G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

248Q

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

249S

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

268T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

271F

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

280M

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

282K

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

288I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

289T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

290T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

291I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

292A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

293I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

294G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

299V

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

301Y

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

304E

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

306S

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

308F

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

309M

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

315Q

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

350V

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

357W

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

359M

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

360Y

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

362R

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

438E

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

440T

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

441A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

442L

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

444A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

445A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

447L

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

448A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

449G

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

450L

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

451A

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

452V

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

454I

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)

455W

N- and C-terminal domain interface
5Y, 6I, 8A, 10D, 13T, 14T, 17R, 19V, 21F, 22D, 25Q, 27I, 43G, 75I, 76G, 77I, 78G, 79I, 80T, 81N, 82Q, 83R, 103W, 104Q, 106R, 109A, 113D, 126K, 129T, 130G, 131L, 132V, 134D, 136Y, 137F, 184Y, 185T, 188S, 189R, 195I, 196K, 198L, 220D, 221S, 222S, 223G, 241A, 242G, 248Q, 249S, 268T, 271F, 280M, 282K, 288I, 289T, 290T, 291I, 292A, 293I, 294G, 299V, 301Y, 304E, 306S, 308F, 309M, 315Q, 350V, 357W, 359M, 360Y, 362R, 438E, 440T, 441A, 442L, 444A, 445A, 447L, 448A, 449G, 450L, 451A, 452V, 454I, 455W
CDD
cd07786 (FGGY_EcGK_like)
metal binding site...

10D

metal binding site
10D, 246D
CDD
cd07786 (FGGY_EcGK_like)

246D

metal binding site
10D, 246D
CDD
cd07786 (FGGY_EcGK_like)
catalytic site cd0...

10D

catalytic site
10D, 13T, 246D
CDD
cd07786 (FGGY_EcGK_like)

13T

catalytic site
10D, 13T, 246D
CDD
cd07786 (FGGY_EcGK_like)

246D

catalytic site
10D, 13T, 246D
CDD
cd07786 (FGGY_EcGK_like)
MgATP binding site...

10D

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

12G

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

13T

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

14T

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

17R

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

266Y

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

267G

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

268T

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

311G

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

312A

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

314V

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

315Q

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

327S

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

328K

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

330T

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

411G

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

412G

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

413A

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

416N

MgATP binding site
10D, 12G, 13T, 14T, 17R, 266Y, 267G, 268T, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)
active site cd07786

10D

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

12G

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

13T

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

14T

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

17R

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

82Q

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

83R

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

84E

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

103W

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

136Y

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

246D

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

247Q

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

266Y

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

267G

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

268T

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

271F

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

311G

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

312A

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

314V

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

315Q

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

327S

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

328K

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

330T

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

411G

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

412G

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

413A

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)

416N

active site
10D, 12G, 13T, 14T, 17R, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 266Y, 267G, 268T, 271F, 311G, 312A, 314V, 315Q, 327S, 328K, 330T, 411G, 412G, 413A, 416N
CDD
cd07786 (FGGY_EcGK_like)
glycerol binding s...

13T

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

82Q

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

83R

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

84E

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

103W

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

136Y

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

246D

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

247Q

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)

271F

glycerol binding site
13T, 82Q, 83R, 84E, 103W, 136Y, 246D, 247Q, 271F
CDD
cd07786 (FGGY_EcGK_like)
homotetramer inter...

33K

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

50M

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

53W

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

54S

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

58G

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

61A

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

62E

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

95K

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

173K

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

176N

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

229N

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)

230L

homotetramer interface
33K, 50M, 53W, 54S, 58G, 61A, 62E, 95K, 173K, 176N, 229N, 230L
CDD
cd07786 (FGGY_EcGK_like)
homodimer interfac...

39Y

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

42E

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

45V

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

104Q

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

309M

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

312A

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

315Q

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

316W

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

319D

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

342G

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

344Y

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

349F

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

362R

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

363G

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

364A

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

365I

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

366L

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

367G

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

368L

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

369T

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

370R

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

374K

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)

377I

homodimer interface
39Y, 42E, 45V, 104Q, 309M, 312A, 315Q, 316W, 319D, 342G, 344Y, 349F, 362R, 363G, 364A, 365I, 366L, 367G, 368L, 369T, 370R, 374K, 377I
CDD
cd07786 (FGGY_EcGK_like)
FBP binding site c...

233A

FBP binding site
233A, 234G, 237R
CDD
cd07786 (FGGY_EcGK_like)

234G

FBP binding site
233A, 234G, 237R
CDD
cd07786 (FGGY_EcGK_like)

237R

FBP binding site
233A, 234G, 237R
CDD
cd07786 (FGGY_EcGK_like)
protein IIAGlc int...

403K

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

405N

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

473C

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

475M

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

477E

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

478E

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

479E

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

480R

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

482N

protein IIAGlc interface
403K, 405N, 473C, 475M, 477E, 478E, 479E, 480R, 482N
CDD
cd07786 (FGGY_EcGK_like)

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006072 glycerol-3-phosphate metabolic process

Molecular Function

GO:0004370 glycerol kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_3022

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component