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Entry type
Status
Per-residue features
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Protein
49185_FusoPortal_Gene_633
Length
437 amino acids
Protein family membership
- Sodium:neurotransmitter symporter (IPR000175)
Homologous superfamilies
-
Homologous superfamily5 - 433
- Sodium:neurotransmitter symporter superfamily (IPR037272)
1
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437
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Residue annotation
-
Na binding site 2 ...20G23I314A317S318S
-
putative substrate...21Aputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)22Aputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)24Gputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)25Lputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)26Gputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)27Nputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)106Yputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)224Fputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)225Tputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)230Gputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)232Aputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)318Sputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)321Nputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like)322Qputative substrate binding site 1
21A, 22A, 24G, 25L, 26G, 27N, 106Y, 224F, 225T, 230G, 232A, 318S, 321N, 322Q
CDD
cd10336 (SLC6sbd_Tyt1-Like) -
Na binding site 1 ...22A27N225T257D
-
putative substrate...29Wputative substrate binding site 2
29W, 30L, 105F, 109V, 112W, 283P, 287F
CDD
cd10336 (SLC6sbd_Tyt1-Like)30Lputative substrate binding site 2
29W, 30L, 105F, 109V, 112W, 283P, 287F
CDD
cd10336 (SLC6sbd_Tyt1-Like)105Fputative substrate binding site 2
29W, 30L, 105F, 109V, 112W, 283P, 287F
CDD
cd10336 (SLC6sbd_Tyt1-Like)109Vputative substrate binding site 2
29W, 30L, 105F, 109V, 112W, 283P, 287F
CDD
cd10336 (SLC6sbd_Tyt1-Like)112Wputative substrate binding site 2
29W, 30L, 105F, 109V, 112W, 283P, 287F
CDD
cd10336 (SLC6sbd_Tyt1-Like)283Pputative substrate binding site 2
29W, 30L, 105F, 109V, 112W, 283P, 287F
CDD
cd10336 (SLC6sbd_Tyt1-Like)287Fputative substrate binding site 2
29W, 30L, 105F, 109V, 112W, 283P, 287F
CDD
cd10336 (SLC6sbd_Tyt1-Like)
GO term prediction
Biological Process
GO:0006836 neurotransmitter transport
Molecular Function
GO:0005328 neurotransmitter:sodium symporter activity
Cellular Component
GO:0016021 integral component of membrane