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Protein

49185_FusoPortal_Gene_858

Length

273 amino acids

Protein family membership

NAD(+) synthetase (IPR003694)
- NH(3)-dependent NAD(+) synthetase (IPR022926)

Homologous superfamilies

Homologous superfamily
3 - 259
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)

1 50 100 150 200 273

Domains and repeats

Domain
13 - 251
NAD/GMP synthase (IPR022310)

1 50 100 150 200 273

Detailed signature matches

IPR014729

Rossmann-like alpha/beta/alpha sandwich fold

G3DSA:3.40.50...

3 - 259

GENE3D
G3DSA:3.40.50.620 (G3DSA:3.40.50.620)

IPR003694

NAD(+) synthetase

TIGR00552

11 - 255

TIGRFAMs
TIGR00552 (TIGR00552)
cd00553 (NAD_synthase)

15 - 248

CDD
cd00553 (NAD_synthase)
PTHR23090 (NH 3 /GL...)

13 - 268

PANTHER
PTHR23090 (NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE)

IPR022926

NH(3)-dependent NAD(+) synthetase

MF_00193 (NadE_ammo...)

7 - 254

HAMAP
MF_00193 (NadE_ammonia_dep)

IPR022310

NAD/GMP synthase

PF02540 (NAD_synthase)

13 - 251

Pfam
PF02540 (NAD_synthase)

no IPR

Unintegrated signatures

Coil

1 - 21

COILS
Coil (Coil)
PTHR23090:SF9 (GLUT...)

13 - 268

PANTHER
PTHR23090:SF9 (GLUTAMINE-DEPENDENT NAD + SYNTHETASE)
SSF52402 (Adenine n...)

4 - 253

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)

Residue annotation

homodimer interfac...

15L

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

18F

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

21E

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

22E

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

85R

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

86S

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

87K

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

88K

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

91I

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

92T

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

95V

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

96D

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

109R

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

113K

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

116R

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

117E

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

119M

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

120S

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

121I

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

123F

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

124D

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

125H

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

127A

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

128K

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

149Q

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

150F

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

153S

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

154A

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

155S

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

156A

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

157V

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

158N

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

161G

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

162D

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

246Y

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)

248R

homodimer interface
15L, 18F, 21E, 22E, 85R, 86S, 87K, 88K, 91I, 92T, 95V, 96D, 109R, 113K, 116R, 117E, 119M, 120S, 121I, 123F, 124D, 125H, 127A, 128K, 149Q, 150F, 153S, 154A, 155S, 156A, 157V, 158N, 161G, 162D, 246Y, 248R
CDD
cd00553 (NAD_synthase)
NAD binding pocket...

33L

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

34G

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

35L

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

36S

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

41S

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

60I

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

61M

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

62M

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

108L

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

112N

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

115A

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

116R

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

118R

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

136T

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

141E

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

146Y

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

147S

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

148T

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

149Q

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

152D

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

187S

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

188A

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

190L

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

199E

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

246Y

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)

247K

NAD binding pocket
33L, 34G, 35L, 36S, 41S, 60I, 61M, 62M, 108L, 112N, 115A, 116R, 118R, 136T, 141E, 146Y, 147S, 148T, 149Q, 152D, 187S, 188A, 190L, 199E, 246Y, 247K
CDD
cd00553 (NAD_synthase)
ATP binding pocket...

34G

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

35L

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

36S

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

40D

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

41S

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

61M

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

62M

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

118R

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

136T

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

165K

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

186P

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)

187S

ATP binding pocket
34G, 35L, 36S, 40D, 41S, 61M, 62M, 118R, 136T, 165K, 186P, 187S
CDD
cd00553 (NAD_synthase)
Mg binding site cd...

36S

Mg binding site
36S, 40D, 141E, 187S
CDD
cd00553 (NAD_synthase)

40D

Mg binding site
36S, 40D, 141E, 187S
CDD
cd00553 (NAD_synthase)

141E

Mg binding site
36S, 40D, 141E, 187S
CDD
cd00553 (NAD_synthase)

187S

Mg binding site
36S, 40D, 141E, 187S
CDD
cd00553 (NAD_synthase)
active-site loop c...

69K

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

183E

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

184K

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

185K

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

186P

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

187S

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

188A

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

189D

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

190L

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

193G

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

194Q

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

195T

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

196D

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

197E

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

198Q

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

199E

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

200L

active-site loop
69K, 183E, 184K, 185K, 186P, 187S, 188A, 189D, 190L, 193G, 194Q, 195T, 196D, 197E, 198Q, 199E, 200L
CDD
cd00553 (NAD_synthase)

GO term prediction

Biological Process

GO:0009435 NAD biosynthetic process

Molecular Function

GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0008795 NAD+ synthase activity

Cellular Component

None predicted.