49185_FusoPortal_Gene_909

Protein

49185_FusoPortal_Gene_909

Length

355 amino acids

Protein family membership

Aminotransferase class IV (IPR001544)
- Branched-chain aminotransferase (IPR033939)
  - Branched-chain amino acid aminotransferase II (IPR005786)

Homologous superfamilies

Homologous superfamily
7 - 350
Aminotransferase-like, PLP-dependent enzymes (IPR036038)

1 50 100 150 200 250 300 355

Domains and repeats

None predicted.

Detailed signature matches

IPR036038

Aminotransferase-like, PLP-dependent enzymes
1. SSF56752 (D-aminoac...)
  
  7 - 350
  
  SUPERFAMILY
  SSF56752 (D-aminoacid aminotransferase-like PLP-dependent enzymes)
IPR001544

Aminotransferase class IV
1. PF01063 (Aminotran_4)
  
  67 - 309
  
  Pfam
  PF01063 (Aminotran_4)
IPR033939

Branched-chain aminotransferase
1. cd01557 (BCAT_beta_...)
  
  53 - 341
  
  CDD
  cd01557 (BCAT_beta_family)
IPR005786

Branched-chain amino acid aminotransferase II
1. TIGR01123
  
  41 - 353
  
  TIGRFAMs
  TIGR01123 (TIGR01123)
2. PIRSF006468 (BCAT1)
  
  1 - 355
  
  PIRSF
  PIRSF006468 (BCAT1)

no IPR

Unintegrated signatures

G3DSA:3.20.10.10

173 - 349

GENE3D
G3DSA:3.20.10.10 (G3DSA:3.20.10.10)
G3DSA:3.30.47...

1 - 172

GENE3D
G3DSA:3.30.470.10 (G3DSA:3.30.470.10)
PTHR11825 (SUBGROUP...)

4 - 351

PANTHER
PTHR11825 (SUBGROUP IIII AMINOTRANSFERASE)
PTHR11825:SF44 (BRA...)

4 - 351

PANTHER
PTHR11825:SF44 (BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE)

Residue annotation

homodimer interfac...

53S

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

54M

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

55S

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

56P

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

57A

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

60V

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

61L

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

62H

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

63Y

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

64A

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

66E

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

68F

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

99R

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

136R

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

138F

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

144V

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

145A

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

146V

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

150P

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

157I

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

196G

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

201S

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

203I

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

207E

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)

221D

homodimer interface
53S, 54M, 55S, 56P, 57A, 60V, 61L, 62H, 63Y, 64A, 66E, 68F, 99R, 136R, 138F, 144V, 145A, 146V, 150P, 157I, 196G, 201S, 203I, 207E, 221D
CDD
cd01557 (BCAT_beta_family)
substrate-cofactor...

63Y

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

68F

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

92R

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

148V

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

194K

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

199Y

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

230E

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

257V

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

258T

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)

300T

substrate-cofactor binding pocket
63Y, 68F, 92R, 148V, 194K, 199Y, 230E, 257V, 258T, 300T
CDD
cd01557 (BCAT_beta_family)
catalytic residue ...

194K

catalytic residue
194K
CDD
cd01557 (BCAT_beta_family)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009081 branched-chain amino acid metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004084 branched-chain-amino-acid transaminase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_909

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component