49185_FusoPortal_Gene_994

Protein

49185_FusoPortal_Gene_994

Length

297 amino acids

Protein family membership

GTP-binding protein Era (IPR005662)

Homologous superfamilies

Homologous superfamily
6 - 202
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Homologous superfamily
178 - 293
K homology domain superfamily, prokaryotic type (IPR009019)
Homologous superfamily
182 - 296
K homology domain-like, alpha/beta (IPR015946)

1 50 100 150 200 250 297

Domains and repeats

Domain
1 - 171
Era-type guanine nucleotide-binding (G) domain (IPR030388)
Domain
1 - 151
Small GTP-binding protein domain (IPR005225)
202 - 282
K Homology domain, type 2 (IPR004044)
Domain
6 - 121
GTP binding domain (IPR006073)

1 50 100 150 200 250 297

Detailed signature matches

IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  6 - 202
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR009019

K homology domain superfamily, prokaryotic type
1. SSF54814 (Prokaryot...)
  
  178 - 293
  
  SUPERFAMILY
  SSF54814 (Prokaryotic type KH domain (KH-domain type II))
IPR015946

K homology domain-like, alpha/beta
1. G3DSA:3.30.30...
  
  182 - 296
  
  GENE3D
  G3DSA:3.30.300.20 (G3DSA:3.30.300.20)
IPR005662

GTP-binding protein Era
1. MF_00367 (GTPase_Era)
  
  1 - 293
  
  HAMAP
  MF_00367 (GTPase_Era)
2. TIGR00436
  
  4 - 276
  
  TIGRFAMs
  TIGR00436 (TIGR00436)
IPR005225

Small GTP-binding protein domain
1. TIGR00231
  
  1 - 151
  
  TIGRFAMs
  TIGR00231 (TIGR00231)
IPR030388

Era-type guanine nucleotide-binding (G) domain
1. cd04163 (Era)
  
  1 - 169
  
  CDD
  cd04163 (Era)
2. PS51713 (G_ERA)
  
  2 - 171
  
  PROSITE profiles
  PS51713 (G_ERA)
IPR006073

GTP binding domain
1. PF01926 (MMR_HSR1)
  
  6 - 121
  
  Pfam
  PF01926 (MMR_HSR1)
2. PR00326 (GTP1OBG)
  
  6 - 26
  
  PRINTS
  PR00326 (GTP1OBG)
  
  73 - 91
  
  PRINTS
  PR00326 (GTP1OBG)
IPR004044

K Homology domain, type 2
1. PS50823 (KH_TYPE_2)
  
  202 - 279
  
  PROSITE profiles
  PS50823 (KH_TYPE_2)
2. PF07650 (KH_2)
  
  205 - 282
  
  Pfam
  PF07650 (KH_2)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

51 - 178

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

2 - 50

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
PTHR42698 (FAMILY N...)

2 - 295

PANTHER
PTHR42698 (FAMILY NOT NAMED)
PTHR42698:SF2 (GTP-...)

2 - 295

PANTHER
PTHR42698:SF2 (GTP-BINDING PROTEIN ERA)

Residue annotation

G1 box cd04163

10G

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)

11R

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)

12P

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)

13N

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)

14V

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)

15G

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)

16K

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)

17S

G1 box
10G, 11R, 12P, 13N, 14V, 15G, 16K, 17S
CDD
cd04163 (Era)
GTP/Mg2+ binding s...

12P

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

13N

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

14V

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

15G

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

16K

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

17S

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

18T

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

32S

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

36G

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

37T

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

38T

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

60G

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

120N

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

121K

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

123D

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

151S

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)

152G

GTP/Mg2+ binding site
12P, 13N, 14V, 15G, 16K, 17S, 18T, 32S, 36G, 37T, 38T, 60G, 120N, 121K, 123D, 151S, 152G
CDD
cd04163 (Era)
Switch I region cd...

25S

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

27K

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

28V

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

29A

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

30I

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

31V

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

32S

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

33D

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

34K

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

35A

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

36G

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

37T

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

38T

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

39R

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

40D

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)

41N

Switch I region
25S, 27K, 28V, 29A, 30I, 31V, 32S, 33D, 34K, 35A, 36G, 37T, 38T, 39R, 40D, 41N
CDD
cd04163 (Era)
G2 box cd04163

38T

G2 box
38T
CDD
cd04163 (Era)
Switch II region c...

56I

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)

57D

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)

58T

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)

59P

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)

60G

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)

61I

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)

81K

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)

82D

Switch II region
56I, 57D, 58T, 59P, 60G, 61I, 81K, 82D
CDD
cd04163 (Era)
G3 box cd04163

57D

G3 box
57D, 58T, 59P, 60G
CDD
cd04163 (Era)

58T

G3 box
57D, 58T, 59P, 60G
CDD
cd04163 (Era)

59P

G3 box
57D, 58T, 59P, 60G
CDD
cd04163 (Era)

60G

G3 box
57D, 58T, 59P, 60G
CDD
cd04163 (Era)
G4 box cd04163

120N

G4 box
120N, 121K, 122I, 123D
CDD
cd04163 (Era)

121K

G4 box
120N, 121K, 122I, 123D
CDD
cd04163 (Era)

122I

G4 box
120N, 121K, 122I, 123D
CDD
cd04163 (Era)

123D

G4 box
120N, 121K, 122I, 123D
CDD
cd04163 (Era)
G5 box cd04163

151S

G5 box
151S, 152G, 153Q
CDD
cd04163 (Era)

152G

G5 box
151S, 152G, 153Q
CDD
cd04163 (Era)

153Q

G5 box
151S, 152G, 153Q
CDD
cd04163 (Era)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003723 RNA binding
GO:0005525 GTP binding

Cellular Component

GO:0005622 intracellular

Filter view on

Entry type

Status

Per-residue features

49185_FusoPortal_Gene_994

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component