9817_FusoPortal_Gene_1085

Protein

9817_FusoPortal_Gene_1085

Length

313 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
7 - 171
Thiamin diphosphate-binding fold (IPR029061)
181 - 313
Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (IPR009014)

1 50 100 150 200 250 313

Domains and repeats

Domain
8 - 156
Transketolase-like, pyrimidine-binding domain (IPR005475)
185 - 305
Transketolase, C-terminal domain (IPR033248)

1 50 100 150 200 250 313

Detailed signature matches

IPR029061

Thiamin diphosphate-binding fold
1. SSF52518 (Thiamin d...)
  
  7 - 171
  
  SUPERFAMILY
  SSF52518 (Thiamin diphosphate-binding fold (THDP-binding))
IPR009014

Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
1. G3DSA:3.40.50...
  
  185 - 313
  
  GENE3D
  G3DSA:3.40.50.920 (G3DSA:3.40.50.920)
2. SSF52922 (TK C-term...)
  
  181 - 313
  
  SUPERFAMILY
  SSF52922 (TK C-terminal domain-like)
IPR005475

Transketolase-like, pyrimidine-binding domain
1. PF02779 (Transket_pyr)
  
  8 - 156
  
  Pfam
  PF02779 (Transket_pyr)
IPR033248

Transketolase, C-terminal domain
1. PF02780 (Transketol...)
  
  185 - 305
  
  Pfam
  PF02780 (Transketolase_C)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

3 - 184

GENE3D
G3DSA:3.40.50.970 (G3DSA:3.40.50.970)
PTHR43825 (FAMILY N...)

7 - 313

PANTHER
PTHR43825 (FAMILY NOT NAMED)
PTHR43825:SF1 (SUBF...)

7 - 313

PANTHER
PTHR43825:SF1 (SUBFAMILY NOT NAMED)
cd07033 (TPP_PYR_DX...)

13 - 165

CDD
cd07033 (TPP_PYR_DXS_TK_like)

Residue annotation

PYR/PP interface c...

27K

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

29V

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

35D

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

52N

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

55N

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

57G

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

58I

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

59M

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

60E

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

61S

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

62N

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

65G

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

66V

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

68S

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

69G

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

70L

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

89R

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

92D

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

93Q

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

119N

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

122T

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

138A

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

139V

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)

160Y

PYR/PP interface
27K, 29V, 35D, 52N, 55N, 57G, 58I, 59M, 60E, 61S, 62N, 65G, 66V, 68S, 69G, 70L, 89R, 92D, 93Q, 119N, 122T, 138A, 139V, 160Y
CDD
cd07033 (TPP_PYR_DXS_TK_like)
dimer interface cd...

35D

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

55N

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

58I

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

59M

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

60E

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

88R

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

89R

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

91F

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

119N

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

121G

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

130A

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

131L

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

133R

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

134T

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)

136P

dimer interface
35D, 55N, 58I, 59M, 60E, 88R, 89R, 91F, 119N, 121G, 130A, 131L, 133R, 134T, 136P
CDD
cd07033 (TPP_PYR_DXS_TK_like)
TPP binding site c...

58I

TPP binding site
58I, 60E, 86A, 89R
CDD
cd07033 (TPP_PYR_DXS_TK_like)

60E

TPP binding site
58I, 60E, 86A, 89R
CDD
cd07033 (TPP_PYR_DXS_TK_like)

86A

TPP binding site
58I, 60E, 86A, 89R
CDD
cd07033 (TPP_PYR_DXS_TK_like)

89R

TPP binding site
58I, 60E, 86A, 89R
CDD
cd07033 (TPP_PYR_DXS_TK_like)

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

9817_FusoPortal_Gene_1085

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component