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Protein

9817_FusoPortal_Gene_1196

Length

332 amino acids

Protein family membership

ADP-L-glycero-D-manno-heptose-6-epimerase (IPR011912)

Homologous superfamilies

Homologous superfamily
2 - 328
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 332

Domains and repeats

Domain
2 - 247
NAD-dependent epimerase/dehydratase (IPR001509)

1 50 100 150 200 250 300 332

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily

SSF51735 (NAD(P)-bi...)

2 - 328

SUPERFAMILY
SSF51735 (NAD(P)-binding Rossmann-fold domains)

IPR011912

ADP-L-glycero-D-manno-heptose-6-epimerase

TIGR02197

2 - 326

TIGRFAMs
TIGR02197 (TIGR02197)
cd05248 (ADP_GME_SDR_e)

1 - 326

CDD
cd05248 (ADP_GME_SDR_e)
MF_01601 (Heptose_e...)

1 - 327

HAMAP
MF_01601 (Heptose_epimerase)

IPR001509

NAD-dependent epimerase/dehydratase

PF01370 (Epimerase)

2 - 247

Pfam
PF01370 (Epimerase)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

1 - 165

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
G3DSA:3.90.25.10

166 - 331

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)
PTHR43103 (FAMILY N...)

2 - 328

PANTHER
PTHR43103 (FAMILY NOT NAMED)
PTHR43103:SF3 (ADP-...)

2 - 328

PANTHER
PTHR43103:SF3 (ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE)

Residue annotation

NADP binding site ...

5T

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

6G

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

9G

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

10M

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

11I

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

30V

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

31D

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

32K

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

38K

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

53R

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

75M

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

76G

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

77A

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

79S

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

88F

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

92N

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

96Y

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

114A

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

115S

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

116S

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

145Y

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

149K

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

171F

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

172F

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

174V

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

181H

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)

182K

NADP binding site
5T, 6G, 9G, 10M, 11I, 30V, 31D, 32K, 38K, 53R, 75M, 76G, 77A, 79S, 88F, 92N, 96Y, 114A, 115S, 116S, 145Y, 149K, 171F, 172F, 174V, 181H, 182K
CDD
cd05248 (ADP_GME_SDR_e)
homopentamer inter...

33L

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

34R

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

36E

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

37E

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

39W

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

42L

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

43R

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

45R

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

46D

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

47Y

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

48A

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

49D

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

50W

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

52D

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

84R

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

85D

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

86G

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

87D

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

90M

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

94Y

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

98K

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

134E

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

140Q

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

141P

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

142L

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

143N

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

144K

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

147Y

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

151I

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

154D

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

155W

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)

158K

homopentamer interface
33L, 34R, 36E, 37E, 39W, 42L, 43R, 45R, 46D, 47Y, 48A, 49D, 50W, 52D, 84R, 85D, 86G, 87D, 90M, 94Y, 98K, 134E, 140Q, 141P, 142L, 143N, 144K, 147Y, 151I, 154D, 155W, 158K
CDD
cd05248 (ADP_GME_SDR_e)
substrate binding ...

81T

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

173N

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

184R

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

185M

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

186A

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

188M

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

191H

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

219R

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)

254F

substrate binding site
81T, 173N, 184R, 185M, 186A, 188M, 191H, 219R, 254F
CDD
cd05248 (ADP_GME_SDR_e)
active site cd05248

93N

active site
93N, 116S, 145Y, 149K
CDD
cd05248 (ADP_GME_SDR_e)

116S

active site
93N, 116S, 145Y, 149K
CDD
cd05248 (ADP_GME_SDR_e)

145Y

active site
93N, 116S, 145Y, 149K
CDD
cd05248 (ADP_GME_SDR_e)

149K

active site
93N, 116S, 145Y, 149K
CDD
cd05248 (ADP_GME_SDR_e)

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0008712 ADP-glyceromanno-heptose 6-epimerase activity
GO:0050661 NADP binding
GO:0050662 coenzyme binding

Cellular Component

None predicted.