9817_FusoPortal_Gene_1202

Protein

9817_FusoPortal_Gene_1202

Length

512 amino acids

Protein family membership

GMP synthase (IPR022955)

Homologous superfamilies

Homologous superfamily
1 - 224
Class I glutamine amidotransferase-like (IPR029062)
225 - 380
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)

1 50 100 150 200 250 300 350 400 450 512

Domains and repeats

Domain
5 - 195
Glutamine amidotransferase (IPR017926)
GMP synthase, glutamine amidotransferase (IPR004739)
201 - 512
GMP synthase, C-terminal (IPR001674)
Domain
196 - 387
NAD/GMP synthase (IPR022310)
GMP synthetase ATP pyrophosphatase domain (IPR025777)

1 50 100 150 200 250 300 350 400 450 512

Detailed signature matches

IPR029062

Class I glutamine amidotransferase-like
1. G3DSA:3.40.50...
  
  1 - 224
  
  GENE3D
  G3DSA:3.40.50.880 (G3DSA:3.40.50.880)
2. SSF52317 (Class I g...)
  
  6 - 198
  
  SUPERFAMILY
  SSF52317 (Class I glutamine amidotransferase-like)
IPR014729

Rossmann-like alpha/beta/alpha sandwich fold
1. G3DSA:3.40.50...
  
  225 - 380
  
  GENE3D
  G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
IPR022955

GMP synthase
1. MF_00344 (GMP_synthase)
  
  3 - 512
  
  HAMAP
  MF_00344 (GMP_synthase)
IPR017926

Glutamine amidotransferase
1. PF00117 (GATase)
  
  8 - 188
  
  Pfam
  PF00117 (GATase)
2. PS51273 (GATASE_TYPE_1)
  
  5 - 195
  
  PROSITE profiles
  PS51273 (GATASE_TYPE_1)
IPR004739

GMP synthase, glutamine amidotransferase
1. cd01742 (GATase1_GM...)
  
  6 - 186
  
  CDD
  cd01742 (GATase1_GMP_Synthase)
2. TIGR00888
  
  6 - 193
  
  TIGRFAMs
  TIGR00888 (TIGR00888)
IPR022310

NAD/GMP synthase
1. PF02540 (NAD_synthase)
  
  201 - 280
  
  Pfam
  PF02540 (NAD_synthase)
IPR025777

GMP synthetase ATP pyrophosphatase domain
1. PS51553 (GMPS_ATP_P...)
  
  196 - 387
  
  PROSITE profiles
  PS51553 (GMPS_ATP_PPASE)
IPR001674

GMP synthase, C-terminal
1. TIGR00884
  
  201 - 512
  
  TIGRFAMs
  TIGR00884 (TIGR00884)
2. cd01997 (GMP_syntha...)
  
  217 - 511
  
  CDD
  cd01997 (GMP_synthase_C)
3. PF00958 (GMP_synt_C)
  
  420 - 511
  
  Pfam
  PF00958 (GMP_synt_C)

no IPR

Unintegrated signatures

G3DSA:3.30.30...

388 - 512

GENE3D
G3DSA:3.30.300.10 (G3DSA:3.30.300.10)
PR00096 (GATASE)

165 - 178

PRINTS
PR00096 (GATASE)

50 - 59

PRINTS
PR00096 (GATASE)

77 - 88

PRINTS
PR00096 (GATASE)
PR00099 (CPSGATASE)

77 - 93

PRINTS
PR00099 (CPSGATASE)

47 - 61

PRINTS
PR00099 (CPSGATASE)

6 - 20

PRINTS
PR00099 (CPSGATASE)
PTHR11922 (GMP SYNT...)

2 - 512

PANTHER
PTHR11922 (GMP SYNTHASE-RELATED)
PTHR11922:SF2 (GMP ...)

2 - 512

PANTHER
PTHR11922:SF2 (GMP SYNTHASE GLUTAMINE-HYDROLYZING)
SSF52402 (Adenine n...)

181 - 433

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)
SSF54810 (GMP synth...)

392 - 512

SUPERFAMILY
SSF54810 (GMP synthetase C-terminal dimerisation domain)

Residue annotation

AMP/PPi binding si...

13S

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

14Q

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

54G

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

55G

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

56P

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

82C

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

83Y

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

131S

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)

169H

AMP/PPi binding site
13S, 14Q, 54G, 55G, 56P, 82C, 83Y, 131S, 169H
CDD
cd01742 (GATase1_GMP_Synthase)
candidate oxyanion...

55G

candidate oxyanion hole
55G, 83Y
CDD
cd01742 (GATase1_GMP_Synthase)

83Y

candidate oxyanion hole
55G, 83Y
CDD
cd01742 (GATase1_GMP_Synthase)
catalytic triad cd...

82C

catalytic triad
82C, 169H, 171E
CDD
cd01742 (GATase1_GMP_Synthase)

169H

catalytic triad
82C, 169H, 171E
CDD
cd01742 (GATase1_GMP_Synthase)

171E

catalytic triad
82C, 169H, 171E
CDD
cd01742 (GATase1_GMP_Synthase)
potential glutamin...

86Q

potential glutamine specificity residues
86Q, 132H, 167Q
CDD
cd01742 (GATase1_GMP_Synthase)

132H

potential glutamine specificity residues
86Q, 132H, 167Q
CDD
cd01742 (GATase1_GMP_Synthase)

167Q

potential glutamine specificity residues
86Q, 132H, 167Q
CDD
cd01742 (GATase1_GMP_Synthase)
ATP Binding subdom...

217K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

218V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

219L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

220L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

221G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

222L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

223S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

224G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

225G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

226V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

227D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

228S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

229S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

230V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

231A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

232A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

233T

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

234L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

235I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

236H

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

237K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

238A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

239I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

240G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

241D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

243L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

244T

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

245C

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

246I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

247F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

248V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

249D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

250T

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

251G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

252L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

253L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

255K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

256D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

257E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

258A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

259K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

260K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

261V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

262M

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

263E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

264V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

265Y

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

276V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

277D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

278A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

279E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

280E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

281R

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

282F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

283L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

284S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

285K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

286L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

287A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

288G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

289V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

290S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

291D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

292P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

293E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

294S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

295K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

296R

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

297K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

298I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

299I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

300G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

301K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

302E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

303F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

304I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

305E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

306V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

307F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

308D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

309E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

310E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

311A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

312A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

313K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

319F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

320L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

321A

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

322Q

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

323G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

324T

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

325I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

326Y

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

327P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

328D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

329V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

330I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

331E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

332S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

333M

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

334S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

343K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

344S

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

345H

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

346H

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

347N

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

348V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

349G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

350G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

351L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

352P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

357F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

358K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

359L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

360L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

361E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

362P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

363L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

364R

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

365E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

366L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

367F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

368K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

369D

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

370E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

371V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

372R

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

373K

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

374V

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

375G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

376R

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

377E

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

378L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

379G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

380I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

381P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

387R

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

388H

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

389P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

390F

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

391P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

392G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

393P

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

394G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

395L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

396G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

397I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

398R

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

399I

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

400L

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)

401G

ATP Binding subdomain
217K, 218V, 219L, 220L, 221G, 222L, 223S, 224G, 225G, 226V, 227D, 228S, 229S, 230V, 231A, 232A, 233T, 234L, 235I, 236H, 237K, 238A, 239I, 240G, 241D, 243L, 244T, 245C, 246I, 247F, 248V, 249D, 250T, 251G, 252L, 253L, 255K, 256D, 257E, 258A, 259K, 260K, 261V, 262M, 263E, 264V, 265Y, 276V, 277D, 278A, 279E, 280E, 281R, 282F, 283L, 284S, 285K, 286L, 287A, 288G, 289V, 290S, 291D, 292P, 293E, 294S, 295K, 296R, 297K, 298I, 299I, 300G, 301K, 302E, 303F, 304I, 305E, 306V, 307F, 308D, 309E, 310E, 311A, 312A, 313K, 319F, 320L, 321A, 322Q, 323G, 324T, 325I, 326Y, 327P, 328D, 329V, 330I, 331E, 332S, 333M, 334S, 343K, 344S, 345H, 346H, 347N, 348V, 349G, 350G, 351L, 352P, 357F, 358K, 359L, 360L, 361E, 362P, 363L, 364R, 365E, 366L, 367F, 368K, 369D, 370E, 371V, 372R, 373K, 374V, 375G, 376R, 377E, 378L, 379G, 380I, 381P, 387R, 388H, 389P, 390F, 391P, 392G, 393P, 394G, 395L, 396G, 397I, 398R, 399I, 400L, 401G
CDD
cd01997 (GMP_synthase_C)
Ligand Binding sit...

221G

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

222L

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

223S

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

225G

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

226V

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

227D

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

228S

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

246I

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

248V

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)

368K

Ligand Binding sites
221G, 222L, 223S, 225G, 226V, 227D, 228S, 246I, 248V, 368K
CDD
cd01997 (GMP_synthase_C)
Dimerization subdo...

410I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

411L

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

412R

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

413E

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

414A

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

415D

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

416D

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

417I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

418F

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

419I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

420E

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

421E

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

422L

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

431V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

432S

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

433Q

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

434A

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

435F

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

436V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

437V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

438L

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

439L

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

440P

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

443S

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

444V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

445G

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

446V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

447M

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

448G

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

449D

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

450E

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

451R

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

452T

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

453Y

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

457A

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

458V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

459L

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

460R

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

461S

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

462A

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

463N

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

464T

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

465I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

466D

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

467F

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

468M

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

469T

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

470A

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

471T

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

472W

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

479F

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

480L

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

481E

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

482R

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

483V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

484S

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

485N

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

486R

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

487I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

489N

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

490E

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

491V

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

492K

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

493G

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

494I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

495N

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

496R

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

497L

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

498T

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

499Y

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

500D

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

501I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

502S

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

503S

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

504K

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

505P

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

506P

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

507A

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

508T

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

509I

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

510E

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

511W

Dimerization subdomain
410I, 411L, 412R, 413E, 414A, 415D, 416D, 417I, 418F, 419I, 420E, 421E, 422L, 431V, 432S, 433Q, 434A, 435F, 436V, 437V, 438L, 439L, 440P, 443S, 444V, 445G, 446V, 447M, 448G, 449D, 450E, 451R, 452T, 453Y, 457A, 458V, 459L, 460R, 461S, 462A, 463N, 464T, 465I, 466D, 467F, 468M, 469T, 470A, 471T, 472W, 479F, 480L, 481E, 482R, 483V, 484S, 485N, 486R, 487I, 489N, 490E, 491V, 492K, 493G, 494I, 495N, 496R, 497L, 498T, 499Y, 500D, 501I, 502S, 503S, 504K, 505P, 506P, 507A, 508T, 509I, 510E, 511W
CDD
cd01997 (GMP_synthase_C)

GO term prediction

Biological Process

GO:0006164 purine nucleotide biosynthetic process
GO:0006177 GMP biosynthetic process

Molecular Function

GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016462 pyrophosphatase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

9817_FusoPortal_Gene_1202

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component