9817_FusoPortal_Gene_1229

Protein

9817_FusoPortal_Gene_1229

Length

248 amino acids

Protein family membership

Clp protease proteolytic subunit /Translocation-enhancing protein TepA (IPR023562)
- ATP-dependent Clp protease proteolytic subunit (IPR001907)

Homologous superfamilies

Homologous superfamily
17 - 184
ClpP/crotonase-like domain superfamily (IPR029045)

1 50 100 150 200 248

Domains and repeats

None predicted.

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  17 - 184
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR023562

Clp protease proteolytic subunit /Translocation-enhancing protein TepA
1. PF00574 (CLP_protease)
  
  55 - 184
  
  Pfam
  PF00574 (CLP_protease)
2. PTHR10381 (ATP-DEPE...)
  
  17 - 183
  
  PANTHER
  PTHR10381 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT)
IPR001907

ATP-dependent Clp protease proteolytic subunit
1. PR00127 (CLPPROTEASEP)
  
  60 - 80
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  91 - 108
  
  PRINTS
  PR00127 (CLPPROTEASEP)

no IPR

Unintegrated signatures

Coil

216 - 243

COILS
Coil (Coil)
G3DSA:3.90.22...

7 - 193

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
PTHR10381:SF23 (SUB...)

17 - 183

PANTHER
PTHR10381:SF23 (SUBFAMILY NOT NAMED)
cd07016 (S14_ClpP_1)

26 - 187

CDD
cd07016 (S14_ClpP_1)

Residue annotation

oligomer interface...

29S

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

31Y

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

47T

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

48E

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

51E

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

66N

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

73F

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

77A

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

80H

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

83K

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

84R

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

88K

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

96V

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

116N

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

118Y

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

124S

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

125W

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

126I

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

127C

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

134D

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

137E

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

139I

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

141M

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

173E

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)

175W

oligomer interface
29S, 31Y, 47T, 48E, 51E, 66N, 73F, 77A, 80H, 83K, 84R, 88K, 96V, 116N, 118Y, 124S, 125W, 126I, 127C, 134D, 137E, 139I, 141M, 173E, 175W
CDD
cd07016 (S14_ClpP_1)
active site residu...

99S

active site residues
99S, 122H, 173E
CDD
cd07016 (S14_ClpP_1)

122H

active site residues
99S, 122H, 173E
CDD
cd07016 (S14_ClpP_1)

173E

active site residues
99S, 122H, 173E
CDD
cd07016 (S14_ClpP_1)

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

9817_FusoPortal_Gene_1229

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component