9817_FusoPortal_Gene_1380

Protein

9817_FusoPortal_Gene_1380

Length

361 amino acids

Protein family membership

Clp protease proteolytic subunit /Translocation-enhancing protein TepA (IPR023562)
- ATP-dependent Clp protease proteolytic subunit (IPR001907)

Homologous superfamilies

Homologous superfamily
5 - 192
ClpP/crotonase-like domain superfamily (IPR029045)

1 50 100 150 200 250 300 361

Domains and repeats

None predicted.

Detailed signature matches

IPR029045

ClpP/crotonase-like domain superfamily
1. SSF52096 (ClpP/crot...)
  
  5 - 192
  
  SUPERFAMILY
  SSF52096 (ClpP/crotonase)
IPR023562

Clp protease proteolytic subunit /Translocation-enhancing protein TepA
1. PTHR10381 (ATP-DEPE...)
  
  293 - 325
  
  PANTHER
  PTHR10381 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT)
  
  9 - 191
  
  PANTHER
  PTHR10381 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT)
2. PF00574 (CLP_protease)
  
  42 - 188
  
  Pfam
  PF00574 (CLP_protease)
IPR001907

ATP-dependent Clp protease proteolytic subunit
1. PR00127 (CLPPROTEASEP)
  
  165 - 184
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  55 - 75
  
  PRINTS
  PR00127 (CLPPROTEASEP)
  
  88 - 105
  
  PRINTS
  PR00127 (CLPPROTEASEP)

no IPR

Unintegrated signatures

Coil

305 - 325

COILS
Coil (Coil)

215 - 235

COILS
Coil (Coil)

130 - 168

COILS
Coil (Coil)
G3DSA:3.90.22...

1 - 198

GENE3D
G3DSA:3.90.226.10 (G3DSA:3.90.226.10)
PTHR10381:SF23 (SUB...)

293 - 325

PANTHER
PTHR10381:SF23 (SUBFAMILY NOT NAMED)

9 - 191

PANTHER
PTHR10381:SF23 (SUBFAMILY NOT NAMED)
cd07016 (S14_ClpP_1)

19 - 186

CDD
cd07016 (S14_ClpP_1)

Residue annotation

oligomer interface...

22R

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

24Y

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

41V

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

42T

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

45K

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

61N

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

68F

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

72A

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

75H

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

78K

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

79R

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

85E

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

93M

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

113G

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

115Y

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

121P

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

122L

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

123M

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

124Y

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

132E

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

135E

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

137I

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

139H

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

169T

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)

171W

oligomer interface
22R, 24Y, 41V, 42T, 45K, 61N, 68F, 72A, 75H, 78K, 79R, 85E, 93M, 113G, 115Y, 121P, 122L, 123M, 124Y, 132E, 135E, 137I, 139H, 169T, 171W
CDD
cd07016 (S14_ClpP_1)
active site residu...

96S

active site residues
96S, 119H, 169T
CDD
cd07016 (S14_ClpP_1)

119H

active site residues
96S, 119H, 169T
CDD
cd07016 (S14_ClpP_1)

169T

active site residues
96S, 119H, 169T
CDD
cd07016 (S14_ClpP_1)

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

9817_FusoPortal_Gene_1380

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component