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Protein

9817_FusoPortal_Gene_142

Length

328 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
101 - 299
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 328

Domains and repeats

Domain
5 - 326
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139)
Domain
110 - 297
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (IPR006140)

1 50 100 150 200 250 300 328

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily

SSF51735 (NAD(P)-bi...)

101 - 299

SUPERFAMILY
SSF51735 (NAD(P)-binding Rossmann-fold domains)

IPR006139

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain

PF00389 (2-Hacid_dh)

5 - 326

Pfam
PF00389 (2-Hacid_dh)

IPR006140

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain

PF02826 (2-Hacid_dh_C)

110 - 297

Pfam
PF02826 (2-Hacid_dh_C)

IPR029752

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1

PS00065 (D_2_HYDROX...)

147 - 174

PROSITE patterns
PS00065 (D_2_HYDROXYACID_DH_1)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

111 - 300

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)

1 - 110

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR43026 (FAMILY N...)

1 - 328

PANTHER
PTHR43026 (FAMILY NOT NAMED)
PTHR43026:SF2 (SUBF...)

1 - 328

PANTHER
PTHR43026:SF2 (SUBFAMILY NOT NAMED)
SSF52283 (Formate/g...)

2 - 133

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)
cd12184 (HGDH_like)

1 - 328

CDD
cd12184 (HGDH_like)

Residue annotation

putative homodimer...

50R

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

100S

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

102N

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

103A

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

106E

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

107L

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

110T

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

113M

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

114N

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

117R

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

122M

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

123V

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

126S

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

138F

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

139S

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

141E

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

142I

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

143R

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

144N

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

162L

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

165G

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

166L

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

266F

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

267F

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

292I

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

294P

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

295H

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

296I

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

297G

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

298S

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

299Y

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

300T

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

301D

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

302E

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)

304L

putative homodimer interface
50R, 100S, 102N, 103A, 106E, 107L, 110T, 113M, 114N, 117R, 122M, 123V, 126S, 138F, 139S, 141E, 142I, 143R, 144N, 162L, 165G, 166L, 266F, 267F, 292I, 294P, 295H, 296I, 297G, 298S, 299Y, 300T, 301D, 302E, 304L
CDD
cd12184 (HGDH_like)
putative ligand bi...

75T

putative ligand binding site
75T, 76V, 77G, 99Y, 234R, 295H, 298S
CDD
cd12184 (HGDH_like)

76V

putative ligand binding site
75T, 76V, 77G, 99Y, 234R, 295H, 298S
CDD
cd12184 (HGDH_like)

77G

putative ligand binding site
75T, 76V, 77G, 99Y, 234R, 295H, 298S
CDD
cd12184 (HGDH_like)

99Y

putative ligand binding site
75T, 76V, 77G, 99Y, 234R, 295H, 298S
CDD
cd12184 (HGDH_like)

234R

putative ligand binding site
75T, 76V, 77G, 99Y, 234R, 295H, 298S
CDD
cd12184 (HGDH_like)

295H

putative ligand binding site
75T, 76V, 77G, 99Y, 234R, 295H, 298S
CDD
cd12184 (HGDH_like)

298S

putative ligand binding site
75T, 76V, 77G, 99Y, 234R, 295H, 298S
CDD
cd12184 (HGDH_like)
putative NAD bindi...

99Y

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

104I

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

151G

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

153G

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

154K

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

155I

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

156G

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

173Y

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

174D

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

175L

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

203H

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

204C

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

205P

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

206Y

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

211N

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

214L

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

232T

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

233A

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

234R

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

258D

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

259V

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

295H

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

297G

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)

298S

putative NAD binding site
99Y, 104I, 151G, 153G, 154K, 155I, 156G, 173Y, 174D, 175L, 203H, 204C, 205P, 206Y, 211N, 214L, 232T, 233A, 234R, 258D, 259V, 295H, 297G, 298S
CDD
cd12184 (HGDH_like)
catalytic site cd1...

234R

catalytic site
234R, 263E, 295H
CDD
cd12184 (HGDH_like)

263E

catalytic site
234R, 263E, 295H
CDD
cd12184 (HGDH_like)

295H

catalytic site
234R, 263E, 295H
CDD
cd12184 (HGDH_like)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

Cellular Component