9817_FusoPortal_Gene_1471

Protein

9817_FusoPortal_Gene_1471

Length

305 amino acids

Protein family membership

Cysteine synthase (IPR005856)
- Cysteine synthase CysK (IPR005859)

Homologous superfamilies

Homologous superfamily
2 - 302
Tryptophan synthase beta subunit-like PLP-dependent enzyme (IPR036052)

1 50 100 150 200 250 305

Domains and repeats

Domain
8 - 293
Pyridoxal-phosphate dependent enzyme (IPR001926)

1 50 100 150 200 250 305

Detailed signature matches

IPR036052

Tryptophan synthase beta subunit-like PLP-dependent enzyme
1. SSF53686 (Tryptopha...)
  
  2 - 302
  
  SUPERFAMILY
  SSF53686 (Tryptophan synthase beta subunit-like PLP-dependent enzymes)
IPR005856

Cysteine synthase
1. TIGR01136
  
  7 - 305
  
  TIGRFAMs
  TIGR01136 (TIGR01136)
IPR005859

Cysteine synthase CysK
1. TIGR01139
  
  7 - 305
  
  TIGRFAMs
  TIGR01139 (TIGR01139)
IPR001926

Pyridoxal-phosphate dependent enzyme
1. PF00291 (PALP)
  
  8 - 293
  
  Pfam
  PF00291 (PALP)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

40 - 137

GENE3D
G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)

138 - 305

GENE3D
G3DSA:3.40.50.1100 (G3DSA:3.40.50.1100)
PTHR10314 (SER/THR ...)

2 - 305

PANTHER
PTHR10314 (SER/THR DEHYDRATASE, TRP SYNTHASE)
PTHR10314:SF133 (SU...)

2 - 305

PANTHER
PTHR10314:SF133 (SUBFAMILY NOT NAMED)
cd01561 (CBS_like)

11 - 301

CDD
cd01561 (CBS_like)

Residue annotation

dimer interface cd...

15M

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

16L

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

17K

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

29F

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

35Y

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

37P

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

79M

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

82A

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

98I

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

99E

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

102Q

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

103L

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

106A

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

107Y

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

162K

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

163D

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

256A

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

257L

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

258K

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

260G

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

261I

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

262L

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

287N

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

297E

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)

300L

dimer interface
15M, 16L, 17K, 29F, 35Y, 37P, 79M, 82A, 98I, 99E, 102Q, 103L, 106A, 107Y, 162K, 163D, 256A, 257L, 258K, 260G, 261I, 262L, 287N, 297E, 300L
CDD
cd01561 (CBS_like)
catalytic residue ...

42K

catalytic residue
42K
CDD
cd01561 (CBS_like)
pyridoxal 5'-phosp...

42K

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

72N

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

175T

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

176G

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

177T

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

178G

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

179G

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

180S

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

220G

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

266S

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

293T

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

294D

pyridoxal 5'-phosphate binding site
42K, 72N, 175T, 176G, 177T, 178G, 179G, 180S, 220G, 266S, 293T, 294D
CDD
cd01561 (CBS_like)

GO term prediction

Biological Process

GO:0006535 cysteine biosynthetic process from serine

Molecular Function

GO:0004124 cysteine synthase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

9817_FusoPortal_Gene_1471

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component