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Protein

9817_FusoPortal_Gene_1778

Length

404 amino acids

Protein family membership

Peptidase M20 (IPR002933)
- Peptidase M20B, tripeptide aminopeptidase (IPR010161)

Homologous superfamilies

Homologous superfamily
206 - 317
Bacterial exopeptidase dimerisation domain (IPR036264)

1 50 100 150 200 250 300 350 404

Domains and repeats

Domain
203 - 297
Peptidase M20, dimerisation domain (IPR011650)

1 50 100 150 200 250 300 350 404

Detailed signature matches

IPR036264

Bacterial exopeptidase dimerisation domain

SSF55031 (Bacterial...)

206 - 317

SUPERFAMILY
SSF55031 (Bacterial exopeptidase dimerisation domain)

IPR002933

Peptidase M20

PF01546 (Peptidase_M20)

136 - 400

Pfam
PF01546 (Peptidase_M20)

IPR010161

Peptidase M20B, tripeptide aminopeptidase

PTHR42994:SF1 (PEPT...)

2 - 403

PANTHER
PTHR42994:SF1 (PEPTIDASE T)
PIRSF037215 (Peptid...)

1 - 404

PIRSF
PIRSF037215 (Peptidase_T)
TIGR01882

1 - 401

TIGRFAMs
TIGR01882 (TIGR01882)
cd03892 (M20_peptT)

1 - 400

CDD
cd03892 (M20_peptT)
MF_00550 (Aminopept...)

1 - 401

HAMAP
MF_00550 (Aminopeptidase_M20)

IPR011650

Peptidase M20, dimerisation domain

PF07687 (M20_dimer)

203 - 297

Pfam
PF07687 (M20_dimer)

IPR001261

ArgE/DapE/ACY1/CPG2/YscS, conserved site

PS00759 (ARGE_DAPE_...)

135 - 174

PROSITE patterns
PS00759 (ARGE_DAPE_CPG2_2)
PS00758 (ARGE_DAPE_...)

70 - 79

PROSITE patterns
PS00758 (ARGE_DAPE_CPG2_1)

no IPR

Unintegrated signatures

G3DSA:3.40.63...

1 - 404

GENE3D
G3DSA:3.40.630.10 (G3DSA:3.40.630.10)
PTHR42994 (FAMILY N...)

2 - 403

PANTHER
PTHR42994 (FAMILY NOT NAMED)
SSF53187 (Zn-depend...)

1 - 207

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

319 - 402

SUPERFAMILY
SSF53187 (Zn-dependent exopeptidases)

Residue annotation

metal binding site...

75H

metal binding site
75H, 137D, 171E, 172E, 194D, 376H
CDD
cd03892 (M20_peptT)

137D

metal binding site
75H, 137D, 171E, 172E, 194D, 376H
CDD
cd03892 (M20_peptT)

171E

metal binding site
75H, 137D, 171E, 172E, 194D, 376H
CDD
cd03892 (M20_peptT)

172E

metal binding site
75H, 137D, 171E, 172E, 194D, 376H
CDD
cd03892 (M20_peptT)

194D

metal binding site
75H, 137D, 171E, 172E, 194D, 376H
CDD
cd03892 (M20_peptT)

376H

metal binding site
75H, 137D, 171E, 172E, 194D, 376H
CDD
cd03892 (M20_peptT)
dimer interface cd...

81T

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

221H

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

222P

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

223G

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

225A

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

226K

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

227N

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

229M

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

231N

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

233I

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

234M

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

237M

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

240N

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

249P

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

250E

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

251H

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

252T

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

253E

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

258F

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

260L

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

261L

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

262N

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

263D

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

264M

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

265K

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

266G

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

267T

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

268V

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

350R

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

376H

dimer interface
81T, 221H, 222P, 223G, 225A, 226K, 227N, 229M, 231N, 233I, 234M, 237M, 240N, 249P, 250E, 251H, 252T, 253E, 258F, 260L, 261L, 262N, 263D, 264M, 265K, 266G, 267T, 268V, 350R, 376H
CDD
cd03892 (M20_peptT)

GO term prediction

Biological Process

GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0008152 metabolic process

Molecular Function

GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0045148 tripeptide aminopeptidase activity

Cellular Component

GO:0005737 cytoplasm