9817_FusoPortal_Gene_2249

Protein

9817_FusoPortal_Gene_2249

Length

1,242 amino acids

Protein family membership

Phosphoribosylformylglycinamidine synthase, FGAM (IPR010141)

Homologous superfamilies

Homologous superfamily
78 - 141
Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily (IPR036604)
191 - 428
PurM-like, N-terminal domain superfamily (IPR036921)
623 - 810
PurM-like, N-terminal domain superfamily (IPR036921)
976 - 1,242
Class I glutamine amidotransferase-like (IPR029062)
Homologous superfamily
415 - 658
PurM-like, C-terminal domain superfamily (IPR036676)
813 - 950
PurM-like, C-terminal domain superfamily (IPR036676)

1 200 400 600 800 1000 1242

Domains and repeats

Domain
439 - 590
PurM-like, C-terminal domain (IPR010918)
981 - 1,242
Glutamine amidotransferase (IPR017926)

1 200 400 600 800 1000 1242

Detailed signature matches

IPR036604

Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily
1. G3DSA:3.30.12...
  
  78 - 141
  
  GENE3D
  G3DSA:3.30.1280.10 (G3DSA:3.30.1280.10)
IPR036921

PurM-like, N-terminal domain superfamily
1. SSF55326 (PurM N-te...)
  
  302 - 428
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  202 - 227
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
  
  629 - 808
  
  SUPERFAMILY
  SSF55326 (PurM N-terminal domain-like)
2. G3DSA:3.30.13...
  
  623 - 810
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
  
  191 - 414
  
  GENE3D
  G3DSA:3.30.1330.10 (G3DSA:3.30.1330.10)
IPR036676

PurM-like, C-terminal domain superfamily
1. SSF56042 (PurM C-te...)
  
  436 - 658
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
  
  814 - 950
  
  SUPERFAMILY
  SSF56042 (PurM C-terminal domain-like)
2. G3DSA:3.90.65...
  
  813 - 948
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
  
  415 - 606
  
  GENE3D
  G3DSA:3.90.650.10 (G3DSA:3.90.650.10)
IPR029062

Class I glutamine amidotransferase-like
1. G3DSA:3.40.50...
  
  978 - 1,242
  
  GENE3D
  G3DSA:3.40.50.880 (G3DSA:3.40.50.880)
2. SSF52317 (Class I g...)
  
  976 - 1,241
  
  SUPERFAMILY
  SSF52317 (Class I glutamine amidotransferase-like)
IPR010141

Phosphoribosylformylglycinamidine synthase, FGAM
1. TIGR01857
  
  4 - 1,241
  
  TIGRFAMs
  TIGR01857 (TIGR01857)
IPR010918

PurM-like, C-terminal domain
1. PF02769 (AIRS_C)
  
  439 - 590
  
  Pfam
  PF02769 (AIRS_C)
IPR017926

Glutamine amidotransferase
1. PS51273 (GATASE_TYPE_1)
  
  981 - 1,242
  
  PROSITE profiles
  PS51273 (GATASE_TYPE_1)

no IPR

Unintegrated signatures

PF13507 (GATase_5)

979 - 1,241

Pfam
PF13507 (GATase_5)
PTHR10099 (PHOSPHOR...)

2 - 1,242

PANTHER
PTHR10099 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
PTHR10099:SF1 (PHOS...)

2 - 1,242

PANTHER
PTHR10099:SF1 (PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE)
cd01740 (GATase1_FG...)

982 - 1,238

CDD
cd01740 (GATase1_FGAR_AT)
cd02203 (PurL_repeat1)

210 - 598

CDD
cd02203 (PurL_repeat1)
cd02204 (PurL_repeat2)

682 - 919

CDD
cd02204 (PurL_repeat2)

Residue annotation

dimerization inter...

316L

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

317L

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

318M

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

319F

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

321N

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

346D

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

356Q

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

359R

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

362G

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

406A

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

417R

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

418M

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)

422A

dimerization interface
316L, 317L, 318M, 319F, 321N, 346D, 356Q, 359R, 362G, 406A, 417R, 418M, 422A
CDD
cd02203 (PurL_repeat1)
ATP binding site c...

342G

ATP binding site
342G, 346D, 404H, 405V, 406A
CDD
cd02203 (PurL_repeat1)

346D

ATP binding site
342G, 346D, 404H, 405V, 406A
CDD
cd02203 (PurL_repeat1)

404H

ATP binding site
342G, 346D, 404H, 405V, 406A
CDD
cd02203 (PurL_repeat1)

405V

ATP binding site
342G, 346D, 404H, 405V, 406A
CDD
cd02203 (PurL_repeat1)

406A

ATP binding site
342G, 346D, 404H, 405V, 406A
CDD
cd02203 (PurL_repeat1)
dimerization inter...

698A

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

699S

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

700A

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

701I

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

703W

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

728K

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

741L

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

744Q

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

747F

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

782K

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

796P

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

797T

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)

801F

dimerization interface
698A, 699S, 700A, 701I, 703W, 728K, 741L, 744Q, 747F, 782K, 796P, 797T, 801F
CDD
cd02204 (PurL_repeat2)
ATP binding site c...

724E

ATP binding site
724E, 728K, 780G, 781G, 782K
CDD
cd02204 (PurL_repeat2)

728K

ATP binding site
724E, 728K, 780G, 781G, 782K
CDD
cd02204 (PurL_repeat2)

780G

ATP binding site
724E, 728K, 780G, 781G, 782K
CDD
cd02204 (PurL_repeat2)

781G

ATP binding site
724E, 728K, 780G, 781G, 782K
CDD
cd02204 (PurL_repeat2)

782K

ATP binding site
724E, 728K, 780G, 781G, 782K
CDD
cd02204 (PurL_repeat2)
putative active si...

1,042G

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,043F

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,047D

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,083C

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,087Q

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,149S

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,150H

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,211M

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,213H

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,214T

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,215E

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)

1,216R

putative active site
1,042G, 1,043F, 1,047D, 1,083C, 1,087Q, 1,149S, 1,150H, 1,211M, 1,213H, 1,214T, 1,215E, 1,216R
CDD
cd01740 (GATase1_FGAR_AT)
catalytic triad cd...

1,083C

catalytic triad
1,083C, 1,213H, 1,215E
CDD
cd01740 (GATase1_FGAR_AT)

1,213H

catalytic triad
1,083C, 1,213H, 1,215E
CDD
cd01740 (GATase1_FGAR_AT)

1,215E

catalytic triad
1,083C, 1,213H, 1,215E
CDD
cd01740 (GATase1_FGAR_AT)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

9817_FusoPortal_Gene_2249

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component