9817_FusoPortal_Gene_2365

Protein

9817_FusoPortal_Gene_2365

Length

257 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)
- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (IPR011286)

Homologous superfamilies

Homologous superfamily
10 - 256
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 257

Domains and repeats

None predicted.

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  10 - 256
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR002347

Short-chain dehydrogenase/reductase SDR
1. PR00080 (SDRFAMILY)
  
  162 - 181
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  142 - 150
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  89 - 100
  
  PRINTS
  PR00080 (SDRFAMILY)
2. PR00081 (GDHRDH)
  
  16 - 33
  
  PRINTS
  PR00081 (GDHRDH)
  
  89 - 100
  
  PRINTS
  PR00081 (GDHRDH)
  
  218 - 238
  
  PRINTS
  PR00081 (GDHRDH)
  
  136 - 152
  
  PRINTS
  PR00081 (GDHRDH)
  
  183 - 200
  
  PRINTS
  PR00081 (GDHRDH)
  
  162 - 181
  
  PRINTS
  PR00081 (GDHRDH)
IPR011286

2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
1. TIGR01832
  
  10 - 257
  
  TIGRFAMs
  TIGR01832 (TIGR01832)
IPR020904

Short-chain dehydrogenase/reductase, conserved site
1. PS00061 (ADH_SHORT)
  
  149 - 177
  
  PROSITE patterns
  PS00061 (ADH_SHORT)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

6 - 255

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PF13561 (adh_short_C2)

24 - 254

Pfam
PF13561 (adh_short_C2)
PTHR42760 (FAMILY N...)

7 - 257

PANTHER
PTHR42760 (FAMILY NOT NAMED)
PTHR42760:SF58 (SUB...)

7 - 257

PANTHER
PTHR42760:SF58 (SUBFAMILY NOT NAMED)
cd05347 (Ga5DH-like...)

10 - 256

CDD
cd05347 (Ga5DH-like_SDR_c)

Residue annotation

NADP binding site ...

21G

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

23N

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

24T

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

25G

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

26L

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

45T

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

46Y

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

47D

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

69A

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

70D

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

71L

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

97N

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

98A

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

99G

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

100T

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

120I

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

147I

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

148A

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

149S

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

162Y

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

166K

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

192P

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

193G

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

194Y

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

195I

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

197T

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

198A

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

199N

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)

200T

NADP binding site
21G, 23N, 24T, 25G, 26L, 45T, 46Y, 47D, 69A, 70D, 71L, 97N, 98A, 99G, 100T, 120I, 147I, 148A, 149S, 162Y, 166K, 192P, 193G, 194Y, 195I, 197T, 198A, 199N, 200T
CDD
cd05347 (Ga5DH-like_SDR_c)
homodimer interfac...

74R

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

105P

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

106L

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

107L

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

108E

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

109Y

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

111D

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

114W

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

115K

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

118M

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

123N

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

126Y

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

127F

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

130Q

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

133A

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

151L

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

152S

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

153F

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

159V

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

160P

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

163T

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

164A

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

167H

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

168G

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

171G

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

172I

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

174K

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

175A

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

176F

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

178N

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

179E

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)

180L

homodimer interface
74R, 105P, 106L, 107L, 108E, 109Y, 111D, 114W, 115K, 118M, 123N, 126Y, 127F, 130Q, 133A, 151L, 152S, 153F, 159V, 160P, 163T, 164A, 167H, 168G, 171G, 172I, 174K, 175A, 176F, 178N, 179E, 180L
CDD
cd05347 (Ga5DH-like_SDR_c)
active site cd05347

121N

active site
121N, 149S, 162Y, 166K
CDD
cd05347 (Ga5DH-like_SDR_c)

149S

active site
121N, 149S, 162Y, 166K
CDD
cd05347 (Ga5DH-like_SDR_c)

162Y

active site
121N, 149S, 162Y, 166K
CDD
cd05347 (Ga5DH-like_SDR_c)

166K

active site
121N, 149S, 162Y, 166K
CDD
cd05347 (Ga5DH-like_SDR_c)

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008678 2-deoxy-D-gluconate 3-dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0051287 NAD binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

9817_FusoPortal_Gene_2365

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component