9817_FusoPortal_Gene_2522

Protein

9817_FusoPortal_Gene_2522

Length

246 amino acids

Protein family membership

Acylneuraminate cytidylyltransferase (IPR003329)
- 3-deoxy-D-manno-octulosonate cytidylyltransferase (IPR004528)

Homologous superfamilies

Homologous superfamily
1 - 243
Nucleotide-diphospho-sugar transferases (IPR029044)

1 50 100 150 200 246

Domains and repeats

None predicted.

Detailed signature matches

IPR029044

Nucleotide-diphospho-sugar transferases
1. G3DSA:3.90.55...
  
  1 - 243
  
  GENE3D
  G3DSA:3.90.550.10 (G3DSA:3.90.550.10)
2. SSF53448 (Nucleotid...)
  
  1 - 241
  
  SUPERFAMILY
  SSF53448 (Nucleotide-diphospho-sugar transferases)
IPR003329

Acylneuraminate cytidylyltransferase
1. PF02348 (CTP_transf_3)
  
  5 - 213
  
  Pfam
  PF02348 (CTP_transf_3)
IPR004528

3-deoxy-D-manno-octulosonate cytidylyltransferase
1. TIGR00466
  
  1 - 232
  
  TIGRFAMs
  TIGR00466 (TIGR00466)
2. MF_00057 (KdsB)
  
  1 - 239
  
  HAMAP
  MF_00057 (KdsB)
3. cd02517 (CMP-KDO-Sy...)
  
  2 - 237
  
  CDD
  cd02517 (CMP-KDO-Synthetase)

no IPR

Unintegrated signatures

PTHR42866 (FAMILY N...)

2 - 240

PANTHER
PTHR42866 (FAMILY NOT NAMED)
PTHR42866:SF2 (3-DE...)

2 - 240

PANTHER
PTHR42866:SF2 (3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL)

Residue annotation

Ligand binding sit...

8P

Ligand binding site
8P, 9S, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

9S

Ligand binding site
8P, 9S, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

10R

Ligand binding site
8P, 9S, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

48A

Ligand binding site
8P, 9S, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

75G

Ligand binding site
8P, 9S, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

96Q

Ligand binding site
8P, 9S, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)

98D

Ligand binding site
8P, 9S, 10R, 48A, 75G, 96Q, 98D
CDD
cd02517 (CMP-KDO-Synthetase)
oligomer interface...

121S

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

138P

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

144I

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

145T

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

146D

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

152L

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

153Y

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

155S

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

156R

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

157S

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

158V

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

159I

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

160P

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

161Y

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

169N

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

194P

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

195L

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

198S

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

199E

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

200S

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

207L

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

208E

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

209N

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

210G

oligomer interface
121S, 138P, 144I, 145T, 146D, 152L, 153Y, 155S, 156R, 157S, 158V, 159I, 160P, 161Y, 169N, 194P, 195L, 198S, 199E, 200S, 207L, 208E, 209N, 210G
CDD
cd02517 (CMP-KDO-Synthetase)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features

9817_FusoPortal_Gene_2522

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component